Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting (Q28506616)

From Wikidata

Jump to navigation Jump to search

scientific journal article

Language	Label	Description	Also known as
English	Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting	scientific journal article

Statements

scholarly article

1 reference

24 January 2017

Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting (English)

1 reference

24 January 2017

Serum response factor

1 reference

GOA release 2020-03-11

T-lymphoma invasion and metastasis-inducing protein 1

1 reference

GOA release 2020-03-11

Rac family small GTPase 1

1 reference

GOA release 2020-03-11

object named as

John Sondek

4

0 references

object named as

Mark A. Lemmon

5

0 references

author name string

Mark A. Baumeister

1

1 reference

24 January 2017

Lenka Martinu

2

1 reference

24 January 2017

Kent L. Rossman

3

1 reference

24 January 2017

Margaret M. Chou

6

1 reference

24 January 2017

language of work or name

0 references

publication date

28 March 2003

1 reference

24 January 2017

Journal of Biological Chemistry

1 reference

24 January 2017

278

1 reference

24 January 2017

11457–11464

1 reference

24 January 2017

13

1 reference

24 January 2017

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Signal-dependent membrane targeting by pleckstrin homology (PH) domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Dbl family guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

A role for Rac in Tiam1-induced membrane ruffling and invasion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

The Dbl family of oncogenes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

The pleckstrin homology domain mediates transformation by oncogenic dbl through specific intracellular targeting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Membrane binding and enzymatic activation of a Dbl homology domain require the neighboring pleckstrin homology domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Distinct roles for DH and PH domains in the Lbc oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Phosphatidylinositol 3-phosphate is generated in phagosomal membranes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

[48] Analysis of phosphoinositide binding by Pleckstrin homology domain from dynamin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Specificity in pleckstrin homology (PH) domain membrane targeting: a role for a phosphoinositide-protein co-operative mechanism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Intracellular regulation. Rac and Bcr regulate phagocytic phoxes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Regulation of proto-Dbl by intracellular membrane targeting and protein stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211901200

21 January 2018

Identifiers

10.1074/JBC.M211901200

0 references

1 reference

24 January 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28506616&oldid=1213614616"