Serum response factor (Q21990643)

http://www.ebi.ac.uk/interpro/protein/Q9JM73

Transcription factor, MADS-box, protein family

1 reference

based on heuristic

inferred from protein domain or family

MADS SRF-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein dimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

DNA-binding transcription factor activity

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Actin dynamics control SRF activity by regulation of its coactivator MAL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

DNA-binding transcription activator activity, RNA polymerase II-specific

9 references

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

11 October 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

11 October 2018

Protein tyrosine phosphatase-like A regulates myoblast proliferation and differentiation through MyoG and the cell cycling signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

11 October 2018

SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Protein tyrosine phosphatase-like A regulates myoblast proliferation and differentiation through MyoG and the cell cycling signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

Regulation of cardiac microRNAs by serum response factor

primary miRNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

serum response element binding

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Actin dynamics control SRF activity by regulation of its coactivator MAL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Promoter function and structure of the growth factor-inducible immediate early gene cyr61

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

11 references

14 February 2019

SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Actin dynamics control SRF activity by regulation of its coactivator MAL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Potentiation of serum response factor activity by a family of myocardin-related transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Identification of Barx2b, a serum response factor-associated homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Bioinformatics and cellular signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

7 references

14 February 2019

Identification of Barx2b, a serum response factor-associated homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

The essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

DNA-binding transcription activator activity, RNA polymerase II-specific

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

11 October 2018

The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

Pitx2 is functionally important in the early stages of vascular smooth muscle cell differentiation

chromatin DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

sequence-specific DNA binding

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

transcription factor binding

3 references

sequence-specific DNA binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

RNA polymerase II-specific DNA-binding transcription factor binding

IBA

1 reference

14 February 2019

Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

DNA-binding transcription factor activity, RNA polymerase II-specific

IPI

IBA

RNA polymerase II general transcription initiation factor activity

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

DNA-binding transcription factor activity, RNA polymerase II-specific

ISO

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

1 January 2018

The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

HOP/NECC1, a novel regulator of mouse trophoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

24 April 2018

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

24 April 2018

HOP/NECC1, a novel regulator of mouse trophoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

24 April 2018

Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

HOP/NECC1, a novel regulator of mouse trophoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

dorsal aorta morphogenesis

IBA

biological process

1 reference

14 February 2019

Restricted inactivation of serum response factor to the cardiovascular system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

bronchus cartilage development

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

muscle cell cellular homeostasis

1 reference

14 February 2019

Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

lung smooth muscle development

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

regulation of water loss via skin

1 reference

14 February 2019

Serum response factor is essential for the proper development of skin epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

cell migration involved in sprouting angiogenesis

3 references

stress fiber assembly

1 reference

14 February 2019

Serum response factor is an essential transcription factor in megakaryocytic maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Serum response factor is an essential transcription factor in megakaryocytic maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

cardiac myofibril assembly

1 reference

14 February 2019

Restricted inactivation of serum response factor to the cardiovascular system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

regulation of cell adhesion

1 reference

14 February 2019

Serum response factor is required for sprouting angiogenesis and vascular integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel context

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

neuron projection development

1 reference

14 February 2019

A nuclear actin function regulates neuronal motility by serum response factor-dependent gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

morphogenesis of an epithelial sheet

1 reference

14 February 2019

Serum response factor is essential for the proper development of skin epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

positive regulation of filopodium assembly

1 reference

14 February 2019

Serum response factor is required for sprouting angiogenesis and vascular integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

primitive streak formation

1 reference

14 February 2019

Serum response factor is essential for mesoderm formation during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

cellular response to glucose stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

heart trabecula formation

1 reference

14 February 2019

Restricted inactivation of serum response factor to the cardiovascular system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

actin filament organization

1 reference

14 February 2019

Serum response factor is required for sprouting angiogenesis and vascular integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

in utero embryonic development

1 reference

14 February 2019

Serum response factor is essential for mesoderm formation during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

branching involved in blood vessel morphogenesis

1 reference

14 February 2019

Serum response factor is required for sprouting angiogenesis and vascular integrity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

trachea cartilage development

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

positive regulation of pri-miRNA transcription by RNA polymerase II

1 reference

14 February 2019

Regulation of cardiac microRNAs by serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

epithelial structure maintenance

1 reference

14 February 2019

Serum response factor is essential for the proper development of skin epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel context

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Serum response factor is essential for the proper development of skin epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

epithelial cell-cell adhesion

1 reference

14 February 2019

Serum response factor is essential for the proper development of skin epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Neuronal migration in the murine rostral migratory stream requires serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

eyelid development in camera-type eye

1 reference

14 February 2019

Serum response factor is essential for the proper development of skin epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

thyroid gland development

1 reference

14 February 2019

Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Serum response factor is essential for mesoderm formation during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

hematopoietic stem cell differentiation

1 reference

14 February 2019

The transcription factor Srf regulates hematopoietic stem cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Serum response factor is essential for mesoderm formation during mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

positive thymic T cell selection

1 reference

14 February 2019

The essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

3 references

14 February 2019

Serum response factor is an essential transcription factor in megakaryocytic maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

The transcription factor Srf regulates hematopoietic stem cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Serum response factor is required for cell contact maintenance but dispensable for proliferation in visceral yolk sac endothelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

Restricted inactivation of serum response factor to the cardiovascular system

sarcomere organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

cardiac vascular smooth muscle cell differentiation

1 reference

14 February 2019

Restricted inactivation of serum response factor to the cardiovascular system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

mRNA transcription by RNA polymerase II

1 reference

14 February 2019

SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

multicellular organism development

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JM73&geneProductId=UniProtKB:Q9JM73

tangential migration from the subventricular zone to the olfactory bulb

1 reference

14 February 2019

Neuronal migration in the murine rostral migratory stream requires serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

contractile actin filament bundle assembly

1 reference

14 February 2019

Restricted inactivation of serum response factor to the cardiovascular system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

bicellular tight junction assembly

1 reference

14 February 2019

Serum response factor is essential for the proper development of skin epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

leukocyte differentiation

1 reference

14 February 2019

The transcription factor Srf regulates hematopoietic stem cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

forebrain development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

Neuronal migration in the murine rostral migratory stream requires serum response factor

hippocampus development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

positive regulation of transcription by RNA polymerase II

10 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Identification of Barx2b, a serum response factor-associated homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

The transcription factor Srf regulates hematopoietic stem cell adhesion

erythrocyte development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

negative regulation of pri-miRNA transcription by RNA polymerase II

1 reference

14 February 2019

Regulation of cardiac microRNAs by serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

1 reference

14 February 2019

Serum response factor is required for cell contact maintenance but dispensable for proliferation in visceral yolk sac endothelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

positive regulation of transcription, DNA-templated

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

regulation of transcription, DNA-templated

1 reference

14 February 2019

Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

actin cytoskeleton organization

3 references

14 February 2019

Serum response factor is essential for the proper development of skin epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Neuronal migration in the murine rostral migratory stream requires serum response factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

14 February 2019

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JM73

Transcription factor, MADS-box

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JM73

MADS SRF-like

1 reference

stated in

InterPro Release 71.0