Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages (Q28505138)

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English	Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages	scientific journal article

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scholarly article

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24 January 2017

Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages (English)

1 reference

24 January 2017

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toll-like receptor

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3-phosphoinositide dependent protein kinase 1

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GOA release 2020-03-11

Jens C Brüning

6

object named as

Jens C. Brüning

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24 January 2017

author name string

Bhagirath Chaurasia

1

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24 January 2017

Jan Mauer

2

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24 January 2017

Linda Koch

3

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24 January 2017

Julia Goldau

4

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24 January 2017

Anja-Sterner Kock

5

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24 January 2017

language of work or name

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publication date

1 September 2010

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24 January 2017

Molecular and Cellular Biology

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24 January 2017

30

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24 January 2017

4354–4366

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24 January 2017

17

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24 January 2017

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation

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TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

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Hsp70 inhibits lipopolysaccharide-induced NF-kappaB activation by interacting with TRAF6 and inhibiting its ubiquitination

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3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

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19 March 2017

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

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19 March 2017

Toll-like receptor signalling

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CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

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IRAK-M is a negative regulator of Toll-like receptor signaling

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Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation

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Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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TRAF6 is a signal transducer for interleukin-1

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Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

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I kappa B: a specific inhibitor of the NF-kappa B transcription factor

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

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The two NF-kappaB activation pathways and their role in innate and adaptive immunity

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Toll-like receptors and innate immunity

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Toll-like receptors: critical proteins linking innate and acquired immunity

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

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TRAF6 distinctively mediates MyD88- and IRAK-1-induced activation of NF-kappaB.

2 references

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Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

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Central insulin action in energy and glucose homeostasis

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Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).

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Toll-like receptor signaling

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Identifiers

10.1128/MCB.00069-10

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24 January 2017

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1 reference

24 January 2017

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