The primary folding defect and rescue of ΔF508 CFTR emerge during translation of the mutant domain (Q28476393)

2

Bertrand

Kleizen

1 reference

29 October 2023

Andre Schmidt

3

Andre

Schmidt

1 reference

29 October 2023

John Richardson

4

John

Richardson

1 reference

29 October 2023

Paraskevi Charitou

5

Paraskevi

Charitou

1 reference

29 October 2023

Philip J Thomas

6

Philip J

Thomas

1 reference

29 October 2023

Ineke Braakman

7

Ineke

Creative Commons Attribution 4.0 International

Braakman

1 reference

29 October 2023

language of work or name

English

0 references

publication date

30 November 2010

0 references

published in

PLOS One

0 references

volume

5

0 references

issue

11

0 references

page(s)

e15458

0 references

copyright license

start time

30 November 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

29 September 2017

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Building an understanding of cystic fibrosis on the foundation of ABC transporter structures

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29 September 2017

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A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The translocation, folding, assembly and redox-dependent degradation of secretory and membrane proteins in semi-permeabilized mammalian cells

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2 June 2018

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Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

2 June 2018

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Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

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2 June 2018

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2 June 2018

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Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.

21 January 2018

1 reference

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The molecular chaperone Hsc70 assists the in vitro folding of the N-terminal nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator.

21 January 2018

1 reference

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Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure

21 January 2018

1 reference

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CFTR is a conductance regulator as well as a chloride channel.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994901

Association of domains within the cystic fibrosis transmembrane conductance regulator

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21152102

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Localization and suppression of a kinetic defect in cystic fibrosis transmembrane conductance regulator folding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21152102

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Limited proteolysis as a probe for arrested conformational maturation of delta F508 CFTR

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21152102