Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models (Q28475093)

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English	Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models	scientific article

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10 February 2020

Delayed treatment with systemic (S)-roscovitine provides neuroprotection and inhibits in vivo CDK5 activity increase in animal stroke models (English)

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10 February 2020

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10 February 2020

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Laurent Meijer

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10 February 2020

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Bénédicte Menn

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10 February 2020

Stéphane Bach

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10 February 2020

Teri L Blevins

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10 February 2020

Mark Campbell

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12 August 2010

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10 February 2020

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10 February 2020

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10 February 2020

e12117

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10 February 2020

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12 August 2010

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Neuroprotection for ischemic stroke: past, present and future

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Neurotoxicity induces cleavage of p35 to p25 by calpain

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Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion

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Roscovitine targets, protein kinases and pyridoxal kinase

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Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors

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Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat

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Update of the stroke therapy academic industry roundtable preclinical recommendations

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29 September 2017

Cell cycle inhibition attenuates microglial proliferation and production of IL-1beta, MIP-1alpha, and NO after focal cerebral ischemia in the rat.

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Drug therapies for stroke and traumatic brain injury often display U-shaped dose responses: occurrence, mechanisms, and clinical implications

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29 September 2017

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29 September 2017

Role of cell cycle proteins in CNS injury

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29 September 2017

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Cell cycle machinery and stroke.

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Synaptic roles of Cdk5: implications in higher cognitive functions and neurodegenerative diseases

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29 September 2017

Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice

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Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

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10 February 2020

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10 February 2020

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10 February 2020

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