Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish (Q28389339)

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English	Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish	scientific article

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21 March 2020

Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish (English)

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21 March 2020

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ichthyotoxicity

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Katrina M. Waters

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21 March 2020

Robyn L Tanguay

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Robert L Tanguay

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21 March 2020

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Derik E Haggard

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Pamela D Noyes

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21 March 2020

Toxicology and Applied Pharmacology

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Triclosan: A Widespread Environmental Toxicant with Many Biological Effects

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The anatomical distribution of genetic associations.

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20 March 2017

Triclosan: current status, occurrence, environmental risks and bioaccumulation potential

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Advanced morphological - behavioral test platform reveals neurodevelopmental defects in embryonic zebrafish exposed to comprehensive suite of halogenated and organophosphate flame retardants

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Human fetal exposure to triclosan and triclocarban in an urban population from Brooklyn, New York

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Identification of metabolites, clinical chemistry markers and transcripts associated with hepatotoxicity

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Short-term exposure to triclosan decreases thyroxine in vivo via upregulation of hepatic catabolism in Young Long-Evans rats

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In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens

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20 March 2017

Urinary concentrations of triclosan in the U.S. population: 2003-2004

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A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene

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20 March 2017

Quantification of Hydroxylated Polybrominated Diphenyl Ethers (OH-BDEs), Triclosan, and Related Compounds in Freshwater and Coastal Systems

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Development of a convenient in vivo hepatotoxin assay using a transgenic zebrafish line with liver-specific DsRed expression

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Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish

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29 September 2017

Ten-year trends in urinary concentrations of triclosan and benzophenone-3 in the general U.S. population from 2003 to 2012.

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Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.

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29 September 2017

The commonly used antimicrobial additive triclosan is a liver tumor promoter

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Update on antibacterial soaps: the FDA takes a second look at triclosans

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Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-action

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

The effect of triclosan on the uterotrophic response to extended doses of ethinyl estradiol in the weanling rat.

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2 June 2018

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2 June 2018

435-bp liver regulatory sequence in the liver fatty acid binding protein (L-FABP) gene is sufficient to modulate liver regional expression in transgenic zebrafish

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2 June 2018

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2 June 2018

Triclosan (TCS) exposure impairs lipid metabolism in zebrafish embryos.

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

Triclosan exposure reduces thyroxine levels in pregnant and lactating rat dams and in directly exposed offspring.

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27 November 2018

Triclosan exposure alters postembryonic development in a Pacific tree frog (Pseudacris regilla) Amphibian Metamorphosis Assay (TREEMA).

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27 November 2018

Potential estrogenic activity of triclosan in the uterus of immature rats and rat pituitary GH3 cells

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27 November 2018

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

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27 November 2018

Triclosan exposure modulates estrogen-dependent responses in the female wistar rat.

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27 November 2018

Influence of clinical factors on the haemolysis marker haptoglobin.

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27 November 2018

Effects of triclosan on various aquatic organisms

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27 November 2018

Effects of triclosan on the early life stages and reproduction of medaka Oryzias latipes and induction of hepatic vitellogenin

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27 November 2018

Formation of the digestive system in zebrafish. I. Liver morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023494

27 November 2018

Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023494

27 November 2018

Aquatic toxicity of triclosan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5023494

27 November 2018

Triclosan in plasma and milk from Swedish nursing mothers and their exposure via personal care products

1 reference

https://pubmed.ncbi.nlm.nih.gov/27538710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FDA pushes makers of antimicrobial soap to prove safety and effectiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/27538710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.TAAP.2016.08.013

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27538710%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27538710%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27538710%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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