Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells (Q28290402)

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Jack L Arbiser

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Shi-Yong Sun

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Majd Zayzafoon

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Peter A S Johnstone

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Masato Fujisawa

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Akinobu Gotoh

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Babette Weksler

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Haiyen E Zhau

Alphastatin downregulates vascular endothelial cells sphingosine kinase activity and suppresses tumor growth in nude mice bearing human gastric cancer xenografts

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language of work or name

English

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publication date

1 April 2007

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published in

Cancer

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volume

109

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issue

7

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page(s)

1279-89

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cites work

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Behavioural pharmacological characteristics of honokiol, an anxiolytic agent present in extracts of Magnolia bark, evaluated by an elevated plus-maze test in mice.

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Angiogenesis inhibition plus chemotherapy for metastatic hormone refractory prostate cancer: history and rationale

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Honokiol: a potent chemotherapy candidate for human colorectal carcinoma

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Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis

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7 January 2021

Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo

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7 January 2021

The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells

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Honokiol induces apoptosis through p53-independent pathway in human colorectal cell line RKO.

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7 January 2021

Down-modulation of Bcl-XL, release of cytochrome c and sequential activation of caspases during honokiol-induced apoptosis in human squamous lung cancer CH27 cells

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Honokiol induces apoptosis via cytochrome c release and caspase activation in activated rat hepatic stellate cells in vitro

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7 January 2021

Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways

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7 January 2021

Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway

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7 January 2021

Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation

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7 January 2021

Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol

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Docetaxel (taxotere) in the treatment of prostate cancer

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Preclinical pharmacology of docetaxel

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Risks and benefits of taxanes in breast and ovarian cancer

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Facile purification of honokiol and its antiviral and cytotoxic properties

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Establishing human prostate cancer cell xenografts in bone: induction of osteoblastic reaction by prostate-specific antigen-producing tumors in athymic and SCID/bg mice using LNCaP and lineage-derived metastatic sublines

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7 January 2021

Protective effects of honokiol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells

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Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production

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Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation

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Free radicals, metals and antioxidants in oxidative stress-induced cancer

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

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Vitamin D enhances caspase-dependent and -independent TNFalpha-induced breast cancer cell death: The role of reactive oxygen species and mitochondria

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Inhibition of p38 mitogen-activated protein kinase reduces TNF-induced activation of NF-kappaB, elicits caspase activity, and enhances cytotoxicity

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Cycloheximide-induced modulation of TNF-mediated cytotoxicity in sensitive and resistant ovarian tumor cells

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A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

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Docetaxel. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of metastatic breast cancer

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Weekly low-dose docetaxel in advanced hormone-resistant prostate cancer patients previously exposed to chemotherapy

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Weekly administration of docetaxel for symptomatic metastatic hormone‐refractory prostate carcinoma

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Docetaxel-based chemotherapy as second-line treatment for paclitaxel-based chemotherapy-resistant hormone-refractory prostate cancer: a pilot study

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Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

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