Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation (Q42834585)

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scientific article published on 29 October 2003

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English	Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation	scientific article published on 29 October 2003

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scholarly article

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Europe PubMed Central

8 November 2017

Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation (English)

1 reference

Europe PubMed Central

8 November 2017

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author name string

Jason A Gustin

1

1 reference

Europe PubMed Central

8 November 2017

Osman N Ozes

2

1 reference

Europe PubMed Central

8 November 2017

Hakan Akca

3

1 reference

Europe PubMed Central

8 November 2017

Roxana Pincheira

4

1 reference

Europe PubMed Central

8 November 2017

Lindsey D Mayo

5

1 reference

Europe PubMed Central

8 November 2017

Qiutang Li

6

1 reference

Europe PubMed Central

8 November 2017

Javier Rivera Guzman

7

1 reference

Europe PubMed Central

8 November 2017

Chandrashekhar K Korgaonkar

8

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Europe PubMed Central

8 November 2017

David B Donner

9

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Europe PubMed Central

8 November 2017

language of work or name

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publication date

29 October 2003

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Europe PubMed Central

8 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

8 November 2017

279

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Europe PubMed Central

8 November 2017

3

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Europe PubMed Central

8 November 2017

1615-1620

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Europe PubMed Central

8 November 2017

NF-kappa B: ten years after

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

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21 January 2018

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Multiple signals converging on NF-kappaB.

1 reference

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21 January 2018

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

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https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Molecular determinants of NF-kappaB-inducing kinase action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Activation of IkappaB kinase beta by protein kinase C isoforms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Ten years of protein kinase B signalling: a hard Akt to follow

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

AKT plays a central role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Phosphorylation of HDM2 by Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Catalysis by a multiprotein IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

IKAP is a scaffold protein of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306976200

21 January 2018

Identifiers

10.1074/JBC.M306976200

1 reference

Europe PubMed Central

8 November 2017

1 reference

Europe PubMed Central

8 November 2017

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