Identification of p122RhoGAP (deleted in liver cancer-1) Serine 322 as a substrate for protein kinase B and ribosomal S6 kinase in insulin-stimulated cells (Q28285843)

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English	Identification of p122RhoGAP (deleted in liver cancer-1) Serine 322 as a substrate for protein kinase B and ribosomal S6 kinase in insulin-stimulated cells	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16338927%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Identification of p122RhoGAP (deleted in liver cancer-1) Serine 322 as a substrate for protein kinase B and ribosomal S6 kinase in insulin-stimulated cells (English)

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10 January 2020

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10 January 2020

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Matthew Wherlock

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10 January 2020

Yoshimi Homma

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10 January 2020

Hitoshi Yagisawa

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10 January 2020

Jeremy M Tavaré

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10 January 2020

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6 December 2005

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10 January 2020

Journal of Biological Chemistry

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10 January 2020

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10 January 2020

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10 January 2020

4762-4770

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10 January 2020

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

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Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM.

1 reference

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Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

1 reference

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21 January 2018

Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase

1 reference

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21 January 2018

Advances in protein kinase B signalling: AKTion on multiple fronts

1 reference

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21 January 2018

Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes

1 reference

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21 January 2018

Analysis of insulin signalling by RNAi-based gene silencing

1 reference

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21 January 2018

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

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21 January 2018

Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects

1 reference

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21 January 2018

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

1 reference

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21 January 2018

Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

1 reference

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21 January 2018

A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

A PLCdelta1-binding protein, p122RhoGAP, is localized in focal adhesions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Reciprocal feedback regulation of insulin receptor and insulin receptor substrate tyrosine phosphorylation by phosphoinositide 3-kinase in primary adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

A PLCdelta1-binding protein, p122/RhoGAP, is localized in caveolin-enriched membrane domains and regulates caveolin internalization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

p90-RSK and Akt may promote rapid phosphorylation/inactivation of glycogen synthase kinase 3 in chemoattractant-stimulated neutrophils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Identification of calcium-regulated heat-stable protein of 24 kDa (CRHSP24) as a physiological substrate for PKB and RSK using KESTREL.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Akt regulates growth by directly phosphorylating Tsc2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Novel insulin-elicited phosphoproteins in adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

TSC2: filling the GAP in the mTOR signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Rheb fills a GAP between TSC and TOR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

1 reference

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21 January 2018

Clostridium botulinum C3 exoenzyme stimulates GLUT4-mediated glucose transport, but not glycogen synthesis, in 3T3-L1 adipocytes--a potential role of rho?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511008200

21 January 2018

Inhibition of insulin-stimulated glucose transport in 3T3-L1 cells by Clostridium difficile toxin B, Clostridium sordellii lethal toxin, and Clostridium botulinum C2 toxin

1 reference

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21 January 2018

Comparative effects of GTPgammaS and insulin on the activation of Rho, phosphatidylinositol 3-kinase, and protein kinase N in rat adipocytes. Relationship to glucose transport

1 reference

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21 January 2018

Roles of insulin, guanosine 5'-[gamma-thio]triphosphate and phorbol 12-myristate 13-acetate in signalling pathways of GLUT4 translocation

1 reference

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DLC-1 operates as a tumor suppressor gene in human non-small cell lung carcinomas

1 reference

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Analysis of DLC-1 expression in human breast cancer.

1 reference

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Identifiers

10.1074/JBC.M511008200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16338927%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16338927%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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