Oxidative stress in neurodegeneration: cause or consequence? (Q28275946)

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31 December 2019

review article

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title

Oxidative stress in neurodegeneration: cause or consequence? (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15298006%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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1

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31 December 2019

author name string

Julie K Andersen

series ordinal

1

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language of work or name

English

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publication date

1 July 2004

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31 December 2019

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31 December 2019

volume

10 Suppl

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31 December 2019

page(s)

S18-25

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Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation.

31 December 2019

cites work

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Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

31 March 2020

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Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease

31 March 2020

1 reference

Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

31 March 2020

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Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

31 March 2020

1 reference

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

31 March 2020

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Protein nitration in Parkinson's disease.

31 March 2020

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Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases

31 March 2020

1 reference

A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease

31 March 2020

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Nitration of tau protein is linked to neurodegeneration in tauopathies

31 March 2020

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Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation

31 March 2020

1 reference

Decrease in peptide methionine sulfoxide reductase in Alzheimer's disease brain.

31 March 2020

1 reference

Parkinson's disease: a disorder due to nigral glutathione deficiency?

31 March 2020

1 reference

Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients.

31 March 2020

1 reference

Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease

31 March 2020

1 reference

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

31 March 2020

1 reference

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

31 March 2020

1 reference

Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis

31 March 2020

1 reference

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

31 March 2020

1 reference

Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice.

31 March 2020

1 reference

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

31 March 2020

1 reference

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

31 March 2020

1 reference

Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.

31 March 2020

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Manganese superoxide dismutase overexpression attenuates MPTP toxicity.

31 March 2020

1 reference

Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity

31 March 2020

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Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

31 March 2020

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Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

31 March 2020

1 reference

Methamphetamine- and 1-methyl-4-phenyl- 1,2,3, 6-tetrahydropyridine-induced dopaminergic neurotoxicity in inducible nitric oxide synthase-deficient mice

31 March 2020

1 reference

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

31 March 2020

1 reference

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

31 March 2020

1 reference

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

31 March 2020

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Minocycline enhances MPTP toxicity to dopaminergic neurons

31 March 2020

1 reference

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

31 March 2020

1 reference

A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group

31 March 2020

1 reference

Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis.

31 March 2020

1 reference

Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

31 March 2020

1 reference

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

31 March 2020

1 reference

Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones

31 March 2020

1 reference

Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis

31 March 2020

1 reference

Hsp70 and Hsp40 improve neurite outgrowth and suppress intracytoplasmic aggregate formation in cultured neuronal cells expressing mutant SOD1.

31 March 2020

1 reference

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

31 March 2020

1 reference

α-Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration

31 March 2020

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Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

31 March 2020

1 reference

Vesicle permeabilization by protofibrillar alpha-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism.

31 March 2020

1 reference

Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease

31 March 2020

1 reference

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

31 March 2020

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

31 March 2020

1 reference

Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease?

31 March 2020

1 reference

Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein

31 March 2020

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4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules

31 March 2020

1 reference

Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

31 March 2020

1 reference

Hydrogen peroxide mediates amyloid beta protein toxicity

31 March 2020

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alpha-synuclein promotes mitochondrial deficit and oxidative stress

31 March 2020

1 reference

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity

31 March 2020

1 reference

Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome

31 March 2020

1 reference

Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis

31 March 2020

1 reference

Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases a

31 March 2020

1 reference

ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis

31 March 2020

1 reference

Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia.

31 March 2020

1 reference

Altered glial function causes neuronal death and increases neuronal susceptibility to 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced toxicity in astrocytic/ventral mesencephalic co-cultures

31 March 2020

1 reference

Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2.

31 March 2020

1 reference

Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression.

31 March 2020

1 reference

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

31 March 2020

1 reference

Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis

31 March 2020

1 reference

Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway

31 March 2020

1 reference

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

31 March 2020

1 reference

MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo

31 March 2020

1 reference

SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease

31 March 2020

1 reference

Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

31 March 2020

1 reference

Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

31 March 2020

1 reference

Apoptosis-inducing neurotoxicity of dopamine and its metabolites via reactive quinone generation in neuroblastoma cells

31 March 2020

1 reference

Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease

31 March 2020

1 reference

Dopamine toxicity in neuroblastoma cells: role of glutathione depletion by L-BSO and apoptosis

31 March 2020

1 reference

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

31 March 2020

1 reference

Pharmacological inactivation of the vesicular monoamine transporter can enhance 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration of midbrain dopaminergic neurons, but not locus coeruleus noradrenergic neurons

31 March 2020

1 reference

Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice.

31 March 2020

1 reference

Murine vesicular monoamine transporter 2: molecular cloning and genomic structure

31 March 2020

1 reference

Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.

31 March 2020

1 reference

Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease.

31 March 2020

1 reference

Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease

31 March 2020

1 reference

Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity. Implications for Parkinson's disease.

31 March 2020

1 reference

Depletion of brain glutathione results in a decrease of glutathione reductase activity; an enzyme susceptible to oxidative damage.

31 March 2020

1 reference

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

31 March 2020

1 reference

Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine.

31 March 2020

1 reference

Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways

31 March 2020

1 reference

Brain iron in the ferrocene-loaded rat: its chelation and influence on dopamine metabolism

31 March 2020

1 reference

Iron acquisition and expression of iron regulatory proteins in the developing brain: manipulation by ethanol exposure, iron deprivation and cellular dysfunction

31 March 2020

1 reference

Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease

31 March 2020

1 reference

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

31 March 2020

1 reference

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

31 March 2020

1 reference

The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis

31 March 2020

1 reference

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

31 March 2020

1 reference

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

31 March 2020

1 reference

Survival in transgenic ALS mice does not vary with CNS glutathione peroxidase activity.

31 March 2020

1 reference

Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival

31 March 2020

1 reference

Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein

31 March 2020

1 reference

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

31 March 2020

1 reference

?True? sporadic ALS associated with a novel SOD-1 mutation

31 March 2020

1 reference

Mutant SOD1 causes motor neuron disease independent of copper chaperone-mediated copper loading

31 March 2020

1 reference

Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRN1434

2 references

798992

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31 December 2019

798992

1 reference

798992

2520546

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2 references

2520546

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15298006%20AND%20SRC:MED&resulttype=core&format=json