α-Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration (Q44418952)

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3 November 2019

title

Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration (English)

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3 November 2019

α-Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration (English)

1 reference

10.1523/JNEUROSCI.23-08-03095.2003

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DOI

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28 December 2023

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Amy B. Manning-Bog

1

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28 December 2023

Alison L. McCormack

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28 December 2023

Maya G. Purisai

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28 December 2023

Laurel M. Bolin

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28 December 2023

Donato A. Di Monte

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language of work or name

English

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publication date

1 April 2003

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3 November 2019

15 April 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12716914

full work available at URL

28 December 2023

https://www.jneurosci.org/content/jneuro/23/8/3095.full.pdf

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http://www.jneurosci.org/cgi/content/abstract/23/8/3095

28 December 2023

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https://europepmc.org/articles/PMC6742319

28 December 2023

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https://doi.org/10.1523/jneurosci.23-08-03095.2003

28 December 2023

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28 December 2023

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28 December 2023

published in

Journal of Neuroscience

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3 November 2019

volume

23

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3 November 2019

issue

8

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3 November 2019

page(s)

3095-3099

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Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

3 November 2019

cites work

1 reference

12 December 2020

4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules

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Synuclein expression is decreased in rat substantia nigra following induction of apoptosis by intrastriatal 6-hydroxydopamine.

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12 December 2020

Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury.

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Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

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12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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12 December 2020

A Drosophila model of Parkinson's disease

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12 December 2020

Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli

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12 December 2020

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity

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12 December 2020

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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12 December 2020

Clinical and pathological features of a Parkinsonian syndrome in a family with an Ala53Thr alpha-synuclein mutation

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12 December 2020

Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins.

1 reference

12 December 2020

Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice

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12 December 2020

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

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12 December 2020

Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease

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12 December 2020

Resistance to stress as a function of age in transgenic Drosophila melanogaster overexpressing Hsp70.

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12 December 2020

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

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12 December 2020

alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells

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12 December 2020

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

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12 December 2020

Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat

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Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

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12 December 2020

Environmental factors in Parkinson's disease

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Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

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Enzymatic/nonenzymatic sources of oxyradicals and regulation of antioxidant defenses.

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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Degradation of oxidized proteins in mammalian cells.

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The Hsp70 and Hsp60 chaperone machines

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

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12 December 2020

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease.

1 reference

12 December 2020

Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development

1 reference

12 December 2020

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

1 reference

12 December 2020

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

1 reference

12 December 2020

10.1523/JNEUROSCI.23-08-03095.2003

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12716914%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12716914%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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