IL-21 enhances NK cell functions and survival in healthy and HIV-infected patients with minimal stimulation of viral replication (Q28271479)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20103765%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

IL-21 enhances NK cell functions and survival in healthy and HIV-infected patients with minimal stimulation of viral replication (English)

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17 January 2020

7

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4

Cécile Tremblay

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17 January 2020

1

Alexandre Iannello

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17 January 2020

Mohamed-Rachid Boulassel

series ordinal

2

object named as

Mohamed-Rachid Boulassel

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3

Suzanne Samarani

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6

Jean-Pierre Routy

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author name string

Emil Toma

series ordinal

5

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17 January 2020

language of work or name

English

0 references

publication date

26 January 2010

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Journal of Leukocyte Biology

17 January 2020

published in

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volume

87

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issue

5

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page(s)

857-867

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Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

17 January 2020

cites work

1 reference

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Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

21 January 2018

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Human CD4+ central and effector memory T cells produce IL-21: effect on cytokine-driven proliferation of CD4+ T cell subsets.

21 January 2018

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A vital role for interleukin-21 in the control of a chronic viral infection

21 January 2018

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Interleukin 21: a key player in lymphocyte maturation

21 January 2018

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IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells

21 January 2018

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The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy

21 January 2018

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Interleukin-21 activates human natural killer cells and modulates their surface receptor expression

21 January 2018

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IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells

21 January 2018

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Antiviral NK cell responses in HIV infection: II. viral strategies for evasion and lessons for immunotherapy and vaccination

21 January 2018

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Cutting edge: increased NK cell activity in HIV-1-exposed but uninfected Vietnamese intravascular drug users

21 January 2018

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Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals

21 January 2018

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Decreased levels of circulating IL-21 in HIV-infected AIDS patients: correlation with CD4+ T-cell counts

21 January 2018

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Dynamics and consequences of IL-21 production in HIV-infected individuals: a longitudinal and cross-sectional study.

21 January 2018

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IL-21 augments natural killer effector functions in chronically HIV-infected individuals

21 January 2018

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MICA antigens stimulate T cell proliferation and cell-mediated cytotoxicity

21 January 2018

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IL-21 induces the functional maturation of murine NK cells

21 January 2018

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Interleukin-21 enhances NK cell activation in response to antibody-coated targets

21 January 2018

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Role of antibody-dependent cell-mediated cytotoxicity in the efficacy of therapeutic anti-cancer monoclonal antibodies.

21 January 2018

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IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

21 January 2018

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Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells

21 January 2018

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Interleukin 7 reduces the levels of spontaneous apoptosis in CD4+ and CD8+ T cells from HIV-1-infected individuals

21 January 2018

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Role of common gamma chain utilizing cytokines for immune reconstitution in HIV infection.

21 January 2018

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Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)

21 January 2018

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Activation of antigen-induced lymphocyte proliferation by interleukin-15 without the mitogenic effect of interleukin-2 that may induce human immunodeficiency virus-1 expression

21 January 2018

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Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules

21 January 2018

1 reference

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Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals

21 January 2018

1 reference

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LFA-1 contributes an early signal for NK cell cytotoxicity.

21 January 2018

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Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses

21 January 2018

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LFA-1 signaling through p44/42 is coupled to perforin degranulation in CD56+CD8+ natural killer cells

21 January 2018

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LFA-1 expression on target cells promotes human immunodeficiency virus type 1 infection and transmission

21 January 2018

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Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: a phase IIa trial.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1189/JLB.1009701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20103765%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference