G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers (Q28268833)

2

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Wendy Zhong

3

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Sree Adhikarakunnathu

4

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Scott Powers

5

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Tim Hoey

6

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Songzhu An

7

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Jianxin Yang

G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity

8

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language of work or name

English

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publication date

19 August 2004

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published in

Oncogene

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volume

23

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issue

37

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page(s)

6299-303

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cites work

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The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

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Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes

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Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB.

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The hypoxic tumour microenvironment and metastatic progression

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A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M

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Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4

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Cloning, sequencing and tissue distribution of two related G protein-coupled receptor candidates expressed prominently in human lung tissue

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G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

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Identification of a putative G protein-coupled receptor induced during activation-induced apoptosis of T cells.

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The cyclic AMP-mediated stimulation of cell proliferation

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Mitogenic pathways regulated by G protein oncogenes

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Cell growth control by G protein-coupled receptors: from signal transduction to signal integration

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Isolation of three novel human genes encoding G protein-coupled receptors

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Identification of a molecular target of psychosine and its role in globoid cell formation

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Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation

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Cloning, characterization, and mapping of human homolog of mouse T-cell death-associated gene

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Proton-sensing G-protein-coupled receptors

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Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3

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7 January 2021

Novel GPCRs and their endogenous ligands: expanding the boundaries of physiology and pharmacology

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G-protein-coupled receptors and signaling networks: emerging paradigms.

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A multiplicity of muscarinic mechanisms: enough signaling pathways to take your breath away

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Transforming G proteins

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Rho proteins and cancer

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

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Vacuolar H(+)-ATPase: functional mechanisms and potential as a target for cancer chemotherapy.

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Expression cloning of oncogenes by retroviral transfer of cDNA libraries

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7 January 2021

Identification of human OGR1, a novel G protein-coupled receptor that maps to chromosome 14

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7 January 2021

G2A is an oncogenic G protein-coupled receptor

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7 January 2021