Stimulation of hTAFII68 (NTD)-mediated transactivation by v-Src (Q28257266)

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Sol Kim

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Jerry Pelletier

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Jungho Kim

Chromosomal translocations in human cancer.

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language of work or name

English

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publication date

23 April 2004

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published in

FEBS Letters

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volume

564

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issue

1-2

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page(s)

188-98

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cites work

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A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

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EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

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Novel oncogenic mutations in the WT1 Wilms' tumor suppressor gene: a t(11;22) fuses the Ewing's sarcoma gene, EWS1, to WT1 in desmoplastic small round cell tumor

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The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein

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Molecular cloning of a novel thyroid/steroid receptor superfamily gene from cultured rat neuronal cells

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Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation

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Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

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Src family kinases in tumor progression and metastasis

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Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

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Smad3: a key player in pathogenetic mechanisms dependent on TGF-beta

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Modulation of EWS/WT1 activity by the v-Src protein tyrosine kinase

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Modification of EWS/WT1 functional properties by phosphorylation

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v-Src and EJ Ras alleviate repression of c-Jun by a cell-specific inhibitor

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Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

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Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells

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Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

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Skeletal and extraskeletal myxoid chondrosarcoma: a comparative clinicopathologic, ultrastructural, and molecular study.

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Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation

21 January 2018

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The N-terminal domain of human TAFII68 displays transactivation and oncogenic properties

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Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes

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Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins

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FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

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Activation of cellular genes by avian RNA tumor viruses

21 January 2018

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Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src.

21 January 2018

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pp60c‐src mediates ERK activation/nuclear localization and PAI‐1 gene expression in response to cellular deformation

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Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway

21 January 2018

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Intracellular signalling mediated by protein-tyrosine kinases: networking through phospholipid metabolism

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A putative modular domain present in diverse signaling proteins

21 January 2018

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Signaling through scaffold, anchoring, and adaptor proteins

21 January 2018

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High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides

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Structure and function of the SH3 domain

21 January 2018

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Crystal structure of a Src-homology 3 (SH3) domain

21 January 2018

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Solution structure of the SH3 domain of Src and identification of its ligand-binding site

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Structural basis for the binding of proline-rich peptides to SH3 domains

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Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

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NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos

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Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

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A novel peptide-SH3 interaction.

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The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif

21 January 2018

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Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

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Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites

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SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl

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The fats of life: the importance and function of protein acylation

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Protein-tyrosine kinases

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21 January 2018

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The genetics of TBP and TBP-related factors

21 January 2018

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Nuclear RNA polymerases: role of general initiation factors and cofactors in eukaryotic transcription

21 January 2018

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Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src

21 January 2018

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21 January 2018

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Relationship between c-src tyrosine kinase activity and the control of glucose transporter gene expression

21 January 2018

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Acylation of proteins with myristic acid occurs cotranslationally

21 January 2018

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Specific and saturable binding of pp60v-src to plasma membranes: evidence for a myristyl-src receptor

21 January 2018

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Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

21 January 2018

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DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma

7 January 2021

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The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

7 January 2021

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Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinase

7 January 2021

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Investigation of factors that influence phosphorylation of pp60c-src on tyrosine 527

7 January 2021

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Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

7 January 2021

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Molecular genetics of chromosome translocations involving EWS and related family members

7 January 2021

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Multiple tropomyosin polypeptides in chicken embryo fibroblasts: differential repression of transcription by Rous sarcoma virus transformation

7 January 2021

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Gene regulation by tyrosine kinases: src protein activates various promoters, including c-fos

7 January 2021

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v-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element

7 January 2021

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c-Abl kinase regulates the protein binding activity of c-Crk

7 January 2021

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Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the protein

7 January 2021

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In vitro synthesis of pp60v-src: myristylation in a cell-free system

7 January 2021

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EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

7 January 2021

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The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homolog

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