Structural basis of integrin-mediated signal transduction (Q28256775)

Europe PubMed Central

title

Structural basis of integrin-mediated signal transduction (English)

0 references

1

Y Takada

0 references

author name string

T Kamata

2

0 references

A Irie

3

0 references

W Puzon-McLaughlin

4

0 references

X P Zhang

Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium

5

0 references

language of work or name

English

0 references

publication date

October 1997

0 references

published in

Matrix Biology

0 references

volume

16

0 references

issue

4

0 references

page(s)

143-51

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Binding of glycoprotein IIIa-derived peptide 217-231 to fibrinogen and von Willebrand factors and its inhibition by platelet glycoprotein IIb/IIIa complex

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

A discrete sequence in a platelet integrin is involved in ligand recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Ligand and cation binding are dual functions of a discrete segment of the integrin β3 subunit: Cation displacement is involved in ligand binding

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Contributions of the I and EF hand domains to the divalent cation-dependent collagen binding activity of the alpha2beta1 integrin

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Identifying the putative metal ion-dependent adhesion site in the beta2 (CD18) subunit required for alphaLbeta2 and alphaMbeta2 ligand interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

VLA proteins in the integrin family: structures, functions, and their role on leukocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

A point mutation in the integrin beta 6 subunit abolishes both alpha v beta 6 binding to fibronectin and receptor localization to focal contacts

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Critical amino acid residues for ligand binding are clustered in a predicted beta-turn of the third N-terminal repeat in the integrin alpha 4 and alpha 5 subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Critical threonine and aspartic acid residues within the I domains of beta 2 integrins for interactions with intercellular adhesion molecule 1 (ICAM-1) and C3bi

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

A novel LFA-1 activation epitope maps to the I domain

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Beta 3 integrin derived peptide 217-230 inhibits fibrinogen binding and platelet aggregation: significance of RGD sequences and fibrinogen A alpha-chain

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

A novel divalent cation-binding site in the A domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Critical residues for ligand binding in an I domain-like structure of the integrin beta1 subunit.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

The A-domain of beta 2 integrin CR3 (CD11b/CD18) is a receptor for the hookworm-derived neutrophil adhesion inhibitor NIF.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

1 reference

7 January 2021

Molecular mapping of functional antibody binding sites of alpha 4 integrin

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Structural interlock between ligand-binding site and stalk-like region of beta1 integrin revealed by a monoclonal antibody recognizing conformation-dependent epitope

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Changing Ligand Specificities of αvβ1 and αvβ3 Integrins by Swapping a Short Diverse Sequence of the β Subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Ligand binding to integrin alphaIIbbeta3 is dependent on a MIDAS-like domain in the beta3 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

A structure prediction for the ligand-binding region of the integrin beta subunit: evidence for the presence of a von Willebrand factor A domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Integrin transmembrane signaling and cytoskeletal control

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021

Alpha 4 beta 1 integrin-dependent cell adhesion is regulated by a low affinity receptor pool that is conformationally responsive to ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2897%2990002-0

7 January 2021