mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease (Q28256208)

ORCID Public Data File 2021

author name string

Claire Lafay-Chebassier

1

0 references

Marc Paccalin

2

0 references

Guylène Page

3

0 references

Stéphanie Barc-Pain

4

0 references

Marie Christine Perault-Pochat

5

0 references

Roger Gil

6

0 references

Laurent Pradier

Journal of Neurochemistry

7

0 references

language of work or name

English

0 references

publication date

July 2005

0 references

published in

0 references

volume

94

0 references

page(s)

215-25

0 references

issue

1

0 references

cites work

PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2005.03187.X

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2005.03187.X

Time-restricted role for dendritic activation of the mTOR-p70 S6K pathway in the induction of late-phase long-term potentiation in the CA1

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2005.03187.X

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2005.03187.X

TSC2 mediates cellular energy response to control cell growth and survival

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2005.03187.X

TOR, a central controller of cell growth

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2005.03187.X

PKR; a sentinel kinase for cellular stress

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2005.03187.X

The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1471-4159.2005.03187.X

The TOR pathway: a target for cancer therapy

20 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Increased cytosolic free calcium in lymphocytes of Alzheimer patients

20 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Zinc inhibits protein synthesis in neurons. Potential role of phosphorylation of translation initiation factor-2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Phosphorylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degeneration in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Eukaryotic initiation factor 2alpha kinase and phosphatase activity during postischemic brain reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

FKBP12-Rapamycin-associated Protein or Mammalian Target of Rapamycin (FRAP/mTOR) Localization in the Endoplasmic Reticulum and the Golgi Apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Ribosomal S6 kinase signaling and the control of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Free intracellular calcium in peripheral cells in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Elevated levels of fragmented DNA nucleosomes in native and activated lymphocytes indicate an enhanced sensitivity to apoptosis in sporadic Alzheimer's disease. Specific differences to vascular dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Differential expression of phosphorylated translation initiation factor 2 alpha in Alzheimer's disease and Creutzfeldt-Jakob's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Diminished mitogen-induced calcium uptake by lymphocytes from Alzheimer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Increased phosphorylation of elongation factor 2 in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Age-dependent decrease in the amount of eukaryotic initiation factor 2 in various rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Alzheimer's disease-associated reduction of polysomal mRNA translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Neuronal and glial calcium signaling in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Lymphocyte oxidative DNA damage and plasma antioxidants in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Mechanisms underlying suppression of protein synthesis induced by transient focal cerebral ischemia in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Cell cycle kinesis in lymphocytes in the diagnosis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Beta-amyloid-induced increase in the resting intracellular calcium concentration gives support to tell Alzheimer lymphocytes from control ones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Synthesis, modifications, and turnover of proteins during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

The target of rapamycin (TOR) proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Impairment of mitogenic activation of peripheral blood lymphocytes in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X

Tissue specific expression of PKR protein kinase in aging B6D2F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2005.03187.X