Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease (Q28252760)

2

object named as

Damian C Crowther

0 references

Lynda Skipper

1 reference

ORCID Public Data File 2021

author name string

Kerri J Kinghorn

1

0 references

Lynda K Sharp

3

0 references

Charlotte Nerelius

4

0 references

Richard L Davis

5

0 references

Howard T Chang

6

0 references

Clare Green

7

0 references

David C Gubb

8

0 references

David A Lomas

Journal of Biological Chemistry

10

0 references

language of work or name

English

0 references

publication date

29 September 2006

0 references

published in

0 references

volume

281

0 references

issue

39

0 references

page(s)

29268-77

0 references

cites work

Plaques, tangles and dementia. A quantitative study.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Distribution of plasma alpha 1-antichymotrypsin levels in Alzheimer disease patients and controls and their genetic controls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Association between conformational mutations in neuroserpin and onset and severity of dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Mutant Neuroserpin (S49P) that causes familial encephalopathy with neuroserpin inclusion bodies is a poor proteinase inhibitor and readily forms polymers in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Latent S49P neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Tissue plasminogen activator is required for corticostriatal long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Neuroserpin, a neuroprotective factor in focal ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator. Implications for the design of low molecular weight substrates and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

A role for oligodendrocyte-derived IGF-1 in trophic support of cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

An immune-responsive Serpin regulates the melanization cascade in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Structural transition of alpha 1-antitrypsin by a peptide sequentially similar to beta-strand s4A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Mapping abeta amyloid fibril secondary structure using scanning proline mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Mixtures of wild-type and a pathogenic (E22G) form of Abeta40 in vitro accumulate protofibrils, including amyloid pores.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Multiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of beta-sheets in Alzheimer's beta-amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Molecular neurology of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Amyloid fibrils from muscle myoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

The mechanism of Z alpha 1-antitrypsin accumulation in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Site-Specific Identification of Non-β-Strand Conformations in Alzheimer's β-Amyloid Fibrils by Solid-State NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

A Kinetic Mechanism for the Polymerization of α1-Antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

Examination of the Structure of the Transthyretin Amyloid Fibril by Image Reconstruction from Electron Micrographs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200

The structure of amyloid fibrils by electron microscopy and X-ray diffraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600690200