Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease (Q28239710)

single-nucleotide polymorphism

Europe PubMed Central

title

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease (English)

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main subject

toll-like receptor

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1 reference

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Nicolas W J Schröder

1

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Ralf R Schumann

series ordinal

2

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language of work or name

English

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publication date

March 2005

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published in

Lancet Infectious Diseases

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volume

5

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page(s)

156-64

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issue

3

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cites work

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Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.

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The Toll-IL-1 receptor adaptor family grows to five members.

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Of mice and men: species variations of Toll-like receptor expression

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MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

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Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

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Toll-like receptor downstream signaling

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Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved

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7 January 2021

Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein

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Lipopolysaccharide binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses

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Single-nucleotide polymorphisms in the public domain: how useful are they?

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A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

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CD14 and toll-like receptor 4: a link between infection and acute coronary events?

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LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria

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High concentrations of lipopolysaccharide-binding protein in serum of patients with severe sepsis or septic shock inhibit the lipopolysaccharide response in human monocytes

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7 January 2021

Gene variants of the bactericidal/permeability increasing protein and lipopolysaccharide binding protein in sepsis patients: gender-specific genetic predisposition to sepsis

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Polymorphisms in the lipopolysaccharide-binding protein and bactericidal/permeability-increasing protein in patients with myocardial infarction

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7 January 2021

A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signaling

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7 January 2021

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

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Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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Mapping of a susceptibility locus for Crohn's disease on chromosome 16

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7 January 2021

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

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7 January 2021

Grain dust, endotoxin, and airflow obstruction

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Effect of inhaled endotoxin on bronchial reactivity in asthmatic and normal subjects

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7 January 2021

Variable airway responsiveness to inhaled lipopolysaccharide

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7 January 2021

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

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7 January 2021

A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Variation in Toll-like receptor 4 and susceptibility to group A meningococcal meningitis in Gambian children

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7 January 2021

Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease

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7 January 2021

Effects of functional Toll-like receptor-4 mutations on the immune response to human and experimental sepsis

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7 January 2021

Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock

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7 January 2021

Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome

1 reference

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7 January 2021

Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Association between the Asp299Gly polymorphisms in the Toll-like receptor 4 and premature births in the Finnish population

1 reference

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7 January 2021

Toll-like Receptor 4 Polymorphisms and Atherogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction*1

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7 January 2021

Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes

1 reference

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7 January 2021

The role of innate immunity in acute allograft rejection after lung transplantation.

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7 January 2021

Toll-like receptors in the pathogenesis of human disease

1 reference

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7 January 2021

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

1 reference

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7 January 2021

Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus

1 reference

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7 January 2021

Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathways

1 reference

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7 January 2021

TLR signaling: an emerging bridge from innate immunity to atherogenesis

1 reference

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7 January 2021

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

1 reference

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7 January 2021

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet

1 reference

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7 January 2021

In Vivo Evidence for a Role of Toll-Like Receptor 4 in the Development of Intimal Lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Chlamydia pneumoniae as an emerging risk factor in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Predominant role of toll-like receptor 2 versus 4 in Chlamydia pneumoniae-induced activation of dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Association of TLR4 mutations and the risk for acute GVHD after HLA-matched-sibling hematopoietic stem cell transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Toll-like receptor 4 polymorphism and severity of atopy in asthmatics

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

A lipopolysaccharide-deficient mutant of Neisseria meningitidis elicits attenuated cytokine release by human macrophages and signals via toll-like receptor (TLR) 2 but not via TLR4/MD2.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Single nucleotide polymorphism--disease relationships: statistical issues for the performance of association studies

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Monocytes heterozygous for the Asp299Gly and Thr399Ile mutations in the Toll-like receptor 4 gene show no deficit in lipopolysaccharide signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Heterozygous toll-like receptor 4 polymorphism does not influence lipopolysaccharide-induced cytokine release in human whole blood.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Systemic responsiveness to lipopolysaccharide and polymorphisms in the toll-like receptor 4 gene in human beings.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden Study.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Rapid and inexpensive real-time PCR for genotyping functional polymorphisms within the Toll-like receptor -2, -4, and -9 genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Lack of association between Toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

The toll-like receptor 2 R753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

A polymorphism in the toll-like receptor 2 is associated with IL-12 production from monocyte in lepromatous leprosy

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Toll-like receptor 2 Arg677Trp polymorphism is associated with susceptibility to tuberculosis in Tunisian patients

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Toll-like receptor 2 as a major gene for asthma in children of European farmers

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case–control disease association studies☆☆This work was supported

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Crohn's disease is associated with a toll-like receptor-9 polymorphism.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

IL10 gene polymorphisms are associated with asthma phenotypes in children

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Role of toll-like receptor 4 mutations in gram-negative septic shock

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

Heterozygous toll-like receptor 2 polymorphism does not affect lipoteichoic acid-induced chemokine and inflammatory responses

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2805%2901308-3

7 January 2021

10.1016/S1473-3099(05)01308-3

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Consolidated OpenCitations Corpus – April 2017

release_d2wionkqbfe2nicnr2pflnd444

1238424

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24 November 2022

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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