Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility (Q35022818)

5 August 2017

Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility (English)

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5 August 2017

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Martin L Hibberd

5

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Bruce Beutler

7

object named as

Bruce Beutler

1 reference

5 August 2017

Michael Levin

6

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Annemiek Dols

3

object named as

Annemiek Dols

1 reference

5 August 2017

Irina Smirnova

1

1 reference

5 August 2017

Navjiwan Mann

2

1 reference

5 August 2017

H H Derkx

4

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5 August 2017

language of work or name

English

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publication date

2 May 2003

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Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

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5 August 2017

100

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5 August 2017

10

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5 August 2017

6075-6080

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High Susceptibility of Strain A Mice to Endotoxin and Endotoxin-Red Blood Cell Mixtures

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Three novel mammalian toll-like receptors: gene structure, expression, and evolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Consed: a graphical tool for sequence finishing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Otitis media incidence and impact on the auditory brain stem response in lipopolysaccharide-nonresponsive C3H/HeJ mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Genetic control of susceptibility to Salmonella typhimurium in mice: role of the LPS gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Genetic control of resistance to infection in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Mouse genetic locus Lps influences susceptibility to Neisseria meningitidis infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

The response of recombinant inbred strains of mice to bacterial lipopolysaccharides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

The genetic mapping of a defective LPS response gene in C3H/HeJ mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156328

The immune response against Francisella tularensis live vaccine strain in Lps(n) and Lps(d) mice

25 October 2018

1 reference

12 December 2020

LPS inhibits the intracellular growth of Legionella pneumophila in thioglycolate elicited murine peritoneal macrophages by iron-dependent, tryptophan-independent, oxygen-independent, and arginine-independent mechanisms

1 reference

12 December 2020

Genetic and environmental influences on premature death in adult adoptees

1 reference

12 December 2020

A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease

1 reference

12 December 2020

Bacteremia and compartmentalization of LPS in meningococcal disease

1 reference

12 December 2020

Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease

1 reference

12 December 2020

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1031605100

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5 August 2017

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5 August 2017

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