A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins (Q28210920)

GOA release 2020-03-11

1 reference

T Brue

5

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Thomas Lamonerie

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author name string

B Lamolet

1

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A M Pulichino

2

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T Lamonerie

3

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Y Gauthier

4

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A Enjalbert

6

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J Drouin

Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome

7

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language of work or name

English

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publication date

23 March 2001

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published in

Cell

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volume

104

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page(s)

849-59

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issue

6

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cites work

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Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.

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Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types

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The PTX family of homeodomain transcription factors during pituitary developments.

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Prenatal ontogenesis of pro-opiomelanocortin in the mouse central nervous system and pituitary gland: an in situ hybridization and immunocytochemical study

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Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation.

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Identification of proopiomelanocortin neurones in rat hypothalamus by in situ cDNA-mRNA hybridization

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Pituitary-specific and hormonally regulated gene expression directed by the rat proopiomelanocortin promoter in transgenic mice.

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A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

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The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis

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In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development

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A model for the development of the hypothalamic-pituitary axis: transcribing the hypophysis

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Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

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Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene

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Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein

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Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

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Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis

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Role of Pitx1 upstream of Tbx4 in specification of hindlimb identity.

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Function of Rieger syndrome gene in left-right asymmetry and craniofacial development

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Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation

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Isolated familial adrenocorticotropin deficiency: prenatal diagnosis by maternal plasma estriol assay

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Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

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Ontogenesis of the three parts of the fetal rat adenohypophysis. A detailed immunohistochemical analysis

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NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin gene

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Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family

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The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity

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Rat and mouse proopiomelanocortin gene sequences target tissue-specific expression to the pituitary gland but not to the hypothalamus of transgenic mice

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Early steps in pituitary organogenesis

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Multistep control of pituitary organogenesis.

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T-box genes: what they do and how they do it.

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Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

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A novel transcription factor, T-bet, directs Th1 lineage commitment

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P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development

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Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development

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Tbx5 and Tbx4 genes determine the wing/leg identity of limb buds.

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Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance luteinizing hormone beta gene transcription

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Pituitary-specific expression and glucocorticoid regulation of a proopiomelanocortin fusion gene in transgenic mice

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The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3.

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Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain

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Transcriptional properties of Ptx1 and Ptx2 isoforms

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Authentic cell-specific and developmentally regulated expression of pro-opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice.

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