Mammalian Numb is a target protein of Mdm2, ubiquitin ligase (Q28184893)

1

0 references

Yasuhiro Miyauchi

2

0 references

Reiko Honda

3

0 references

Hirofumi Tanaka

Biochemical and Biophysical Research Communications

4

0 references

language of work or name

English

0 references

publication date

21 March 2003

0 references

published in

0 references

volume

302

0 references

issue

4

0 references

page(s)

869-72

0 references

cites work

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

The ubiquitin-proteasome proteolytic pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

The Mdm2 oncoprotein interacts with the cell fate regulator Numb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Asymmetric segregation of Numb and Prospero during cell division

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Siah-1 binds and regulates the function of Numb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2900282-1