NK4 (HGF-antagonist/angiogenesis inhibitor) in cancer biology and therapeutics (Q28181973)

Molecular cloning and expression of human hepatocyte growth factor

Europe PubMed Central

title

NK4 (HGF-antagonist/angiogenesis inhibitor) in cancer biology and therapeutics (English)

0 references

main subject

angiogenesis inhibitor

1 reference

Kunio Matsumoto

1

0 references

Toshikazu Nakamura

series ordinal

2

0 references

language of work or name

English

0 references

publication date

April 2003

0 references

published in

Cancer Science

0 references

volume

94

0 references

issue

4

0 references

page(s)

321-7

0 references

cites work

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01440.X

Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase

22 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01440.X

Association of the HGF/SF receptor, c-met, with the cell-surface adhesion molecule, E-cadherin, and catenins in human tumor cells

22 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01440.X

Selective tumorigenesis in non-parenchymal liver epithelial cell lines by hepatocyte growth factor transfection

22 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01440.X

Angiostatin binds ATP synthase on the surface of human endothelial cells

22 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2003.TB01440.X

Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancer

22 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Hepatocyte growth factor (HGF) as a tissue organizer for organogenesis and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Induction of tyrosine phosphorylation and translocation of ezrin by hepatocyte growth factor/scatter factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Regulation of endothelial CD44 expression and endothelium-tumour cell interactions by hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Involvement of hepatocyte growth factor in increased integrin expression on HepG2 cells triggered by adhesion to endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Activating mutations for the met tyrosine kinase receptor in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Kringle 5 of plasminogen is a novel inhibitor of endothelial cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Prothrombin kringle-2 domain has a growth inhibitory activity against basic fibroblast growth factor-stimulated capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Expression of HGF/NK4 in ovarian cancer cells suppresses intraperitoneal dissemination and extends host survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Targeting angiogenesis and HGF function using an adenoviral vector expressing the HGF antagonist NK4 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Tumor suppression effect using NK4, a molecule acting as an antagonist of HGF, on human gastric carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

Intraperitoneal injection of adenovirus-mediated NK4 gene suppresses peritoneal dissemination of pancreatic cancer cell line AsPC-1 in nude mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X

In Vivo Activation of met Tyrosine Kinase by Heterodimeric Hepatocyte Growth Factor Molecule Promotes Angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01440.X