Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase (Q28286701)

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

Europe PubMed Central

title

Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase (English)

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author name string

C Birchmeier

series ordinal

1

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E Gherardi

series ordinal

2

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language of work or name

English

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publication date

October 1998

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published in

Trends in Cell Biology

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volume

8

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page(s)

404-10

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issue

10

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cites work

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Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement

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Evidence for the identity of human scatter factor and human hepatocyte growth factor

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Molecular cloning and expression of human hepatocyte growth factor

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Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor

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Purification and characterization of a newly identified growth factor specific for epithelial cells

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Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

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A fibroblast-derived tumor cytotoxic factor/F-TCF(hepatocyte growth factor/HGF) has multiple functions in vitro

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Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons

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Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP)

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Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor

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Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity

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Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

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Identification of the ron gene product as the receptor for the human macrophage stimulating protein

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Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells

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Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo

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Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2.

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Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2.

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Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor

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Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development

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Mechanism of met oncogene activation

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

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Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development

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Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase.

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Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

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Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility

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Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

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Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

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Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

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Scatter factor/hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo

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Regulation and function of SF/HGF during migration of limb muscle precursor cells in chicken.

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Pax3 modulates expression of the c-Met receptor during limb muscle development

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Hepatocyte growth factor activates quiescent skeletal muscle satellite cells in vitro

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A natural hepatocyte growth factor/scatter factor autocrine loop in myoblast cells and the effect of the constitutive Met kinase activation on myogenic differentiation

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Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development

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Scatter factor/hepatocyte growth factor is essential for liver development

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Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

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Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros

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Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

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Activation of Met tyrosine kinase by hepatocyte growth factor is essential for internal organogenesis in Xenopus embryo.

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Hepatocyte growth factor is a mitogen for Schwann cells and is present in neurofibromas

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Expression of the met/hepatocyte growth factor/scatter factor receptor and its ligand during differentiation of murine P19 embryonal carcinoma cells

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Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons.

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Multiple roles for hepatocyte growth factor in sympathetic neuron development.

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The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator

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Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

3016774

3016774

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference