GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2 (Q28181052)

1

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Hong Ma

2

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Ella Bossy-Wetzel

3

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Stuart A Lipton

4

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Zhuohua Zhang

5

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Gen-Sheng Feng

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

5 September 2003

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published in

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volume

278

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page(s)

34641-53

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issue

36

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cites work

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Essential role for Gab2 in the allergic response

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Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

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Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

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Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

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Activated ERK2 interacts with and phosphorylates the docking protein GAB1.

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Rho GTPases in neuronal morphogenesis

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Rho proteins, PI 3-kinases, and monocyte/macrophage motility

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A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoprotein

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The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

21 January 2018

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Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules

21 January 2018

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