Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita (Q28138285)

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S P Tenbaum

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U Dressel

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D Thormeyer

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R Renkawitz

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A Baniahmad

Journal of Biological Chemistry

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language of work or name

English

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publication date

17 March 2000

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published in

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volume

275

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page(s)

7662-7

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issue

11

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cites work

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Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

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A role for nucleosome assembly in both silencing and activation of the Xenopus TR beta A gene by the thyroid hormone receptor

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Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression

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The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing

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A transcriptional co-repressor that interacts with nuclear hormone receptors

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Transcriptional silencing by unliganded thyroid hormone receptor beta requires a soluble corepressor that interacts with the ligand-binding domain of the receptor

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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

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An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

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Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism

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DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis

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Adrenal hypoplasia congenita with hypogonadotropic hypogonadism: evidence that DAX-1 mutations lead to combined hypothalmic and pituitary defects in gonadotropin production

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Expression of DAX-1, the gene responsible for X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism, in the hypothalamic-pituitary-adrenal/gonadal axis

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DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita

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Dax1 antagonizes Sry action in mammalian sex determination

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Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

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Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1

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Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone

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Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

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tau4/tau c/AF-2 of the thyroid hormone receptor relieves silencing of the retinoic acid receptor silencer core independent of both tau4 activation function and full dissociation of corepressors

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DAX1 mutations map to putative structural domains in a deduced three-dimensional model

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Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses

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Truncation at the C-terminus of the DAX-1 protein impairs its biological actions in patients with X-linked adrenal hypoplasia congenita

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New frameshift mutation in the DAX-1 gene in a patient with X-linked adrenal hypoplasia and hypogonadotropic hypogonadism

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release_46xo6fhq35ezfc6wyetbgqdoyy

21 January 2018

Identifiers

DOI

10.1074/JBC.275.11.7662

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Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/46xo6fhq35ezfc6wyetbgqdoyy