Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily (Q24554508)

GOA release 2020-03-11

Alien Dmel_CG9556

1 reference

GOA release 2020-03-11

U Dressel

1

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author name string

D Thormeyer

2

0 references

B Altincicek

3

0 references

A Paululat

4

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M Eggert

5

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S Schneider

6

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S P Tenbaum

7

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R Renkawitz

8

0 references

A Baniahmad

Molecular and Cellular Biology

9

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language of work or name

English

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publication date

May 1999

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published in

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volume

19

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issue

5

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page(s)

3383-94

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cites work

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TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1

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A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein

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Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

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Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: physical association is dependent on the E region of the orphan receptors

24 March 2017

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Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

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KAP-1, a novel corepressor for the highly conserved KRAB repression domain

24 March 2017

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Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

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TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors

24 March 2017

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NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli

24 March 2017

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Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

24 March 2017

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GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors

24 March 2017

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Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression

24 March 2017

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Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

24 March 2017

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The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing

24 March 2017

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Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor

24 March 2017

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Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor

24 March 2017

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Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription

24 March 2017

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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

24 March 2017

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Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

24 March 2017

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A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor

24 March 2017

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Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

24 March 2017

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Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

24 March 2017

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

24 March 2017

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A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

24 March 2017

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The nuclear receptor superfamily: the second decade

24 March 2017

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Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

24 March 2017

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Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters

24 March 2017

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The glucocorticoid receptor is associated with the RNA-binding nuclear matrix protein hnRNP U

24 March 2017

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Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

24 March 2017

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Histone deacetylase activity is required for full transcriptional repression by mSin3A

24 March 2017

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

24 March 2017

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Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

24 March 2017

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The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18

24 March 2017

1 reference

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A transcriptional co-repressor that interacts with nuclear hormone receptors

24 March 2017

1 reference

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

The RXR heterodimers and orphan receptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Role of CBP/P300 in nuclear receptor signalling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Steroid hormone receptors: many actors in search of a plot

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Cell-specific inhibition of retinoic acid receptor-alpha silencing by the AF2/tau c activation domain can be overcome by the corepressor SMRT, but not by N-CoR.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Multiple receptor interaction domains of GRIP1 function in synergy

27 September 2017

1 reference

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Characterization of receptor interaction and transcriptional repression by the corepressor SMRT.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

tau4/tau c/AF-2 of the thyroid hormone receptor relieves silencing of the retinoic acid receptor silencer core independent of both tau4 activation function and full dissociation of corepressors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Transcriptional silencing by unliganded thyroid hormone receptor beta requires a soluble corepressor that interacts with the ligand-binding domain of the receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Identification of a domain required for oncogenic activity and transcriptional suppression by v-erbA and thyroid-hormone receptor alpha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Two silencing sub-domains of v-erbA synergize with each other, but not with RXR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Ligand modulates the interaction of thyroid hormone receptor beta with the basal transcription machinery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

A role for nucleosome assembly in both silencing and activation of the Xenopus TR beta A gene by the thyroid hormone receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Transcriptional repression in eukaryotes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Ecdysterone regulatory elements function as both transcriptional activators and repressors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Active repression mechanisms of eukaryotic transcription repressors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Nuclear receptor coactivators and corepressors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Functional ecdysone receptor is the product of EcR and Ultraspiracle genes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Nuclear receptors: structure, function and involvement in disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

A structural role for hormone in the thyroid hormone receptor.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

Erythroblast cell lines transformed by a temperature-sensitive mutant of avian erythroblastosis virus: a model system to study erythroid differentiation in vitro.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84131

The Drosophila gene alien is expressed in the muscle attachment sites during embryogenesis and encodes a protein highly conserved between plants, Drosophila and vertebrates.

30 May 2018

1 reference

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Enhancer and silencer elements within the first intron mediate the transcriptional regulation of the beta 3 tubulin gene by 20-hydroxyecdysone in Drosophila Kc cells.

28 November 2018

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Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

28 November 2018

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A rapid method combining a functional test of fusion proteins in vivo and their purification

28 November 2018

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12 December 2020

Stoichiometric and steric principles governing repression by nuclear hormone receptors

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12 December 2020

Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor

1 reference

12 December 2020

Nuclear receptors spring into action

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12 December 2020

At least three subdomains of v-erbA are involved in its silencing function

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12 December 2020

Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors

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12 December 2020

Transcriptional repression of eukaryotic promoters

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Crossref

https://api.crossref.org/works/10.1128%2FMCB.19.5.3383

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1128/MCB.19.5.3383

1 reference

2497231

1259498

1 reference

1259498

2497231

1 reference

1 reference

1 reference