The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability (Q28116817)

regulation of mRNA stability

GOA release 2020-03-11

1 reference

Poly(rC) binding protein 4

GOA release 2020-03-11

1 reference

Creative Commons Attribution-NonCommercial 2.5 Generic

GOA release 2020-03-11

1 reference

Ariane Scoumanne

1

1 reference

4 January 2017

Seong Jun Cho

series ordinal

2

1 reference

4 January 2017

Jin Zhang

series ordinal

3

1 reference

4 January 2017

Xinbin Chen

series ordinal

4

1 reference

4 January 2017

language of work or name

English

0 references

publication date

1 January 2011

1 reference

4 January 2017

Nucleic Acids Research

1 reference

4 January 2017

39

1 reference

4 January 2017

213–224

1 reference

4 January 2017

1

1 reference

4 January 2017

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript

20 March 2017

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Identification of two KH domain proteins in the alpha-globin mRNP stability complex

20 March 2017

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20 March 2017

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MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M

20 March 2017

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HuR regulates p21 mRNA stabilization by UV light

20 March 2017

1 reference

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Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein

20 March 2017

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Heterogeneous nuclear ribonucleoprotein K is a transcription factor

20 March 2017

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Examination of the expanding pathways for the regulation of p21 expression and activity

20 March 2017

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WAF1, a potential mediator of p53 tumor suppression

20 March 2017

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RNA-binding proteins in human genetic disease

20 March 2017

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Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation

20 March 2017

1 reference

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A set of highly conserved RNA-binding proteins, alphaCP-1 and alphaCP-2, implicated in mRNA stabilization, are coexpressed from an intronless gene and its intron-containing paralog

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

20 March 2017

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RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability

21 January 2018

1 reference

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p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint

29 September 2017

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The ups and downs of p53: understanding protein dynamics in single cells

29 September 2017

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Poly(C)-binding proteins as transcriptional regulators of gene expression

29 September 2017

1 reference

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Sophisticated framework between cell cycle arrest and apoptosis induction based on p53 dynamics

29 September 2017

1 reference

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Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest

29 September 2017

1 reference

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A proteomics approach for identification of single strand DNA-binding proteins involved in transcriptional regulation of mouse mu opioid receptor gene

29 September 2017

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Structure and function of KH domains

29 September 2017

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Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene

29 September 2017

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Molecular analysis of deletions in human chromosome 3p21 and the role of resident cancer genes in disease

29 September 2017

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The epithelial cell transforming sequence 2, a guanine nucleotide exchange factor for Rho GTPases, is repressed by p53 via protein methyltransferases and is required for G1-S transition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.

29 September 2017

1 reference

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hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage

29 September 2017

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The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21WAF-1.

29 September 2017

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hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation

29 September 2017

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Genomewide production of multipurpose alleles for the functional analysis of the mouse genome

29 September 2017

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Prostaglandin A2-mediated stabilization of p21 mRNA through an ERK-dependent pathway requiring the RNA-binding protein HuR.

29 September 2017

1 reference

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Alpha CP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant alpha CP-4a, is underexpressed in lung cancer.

29 September 2017

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Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo

29 September 2017

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The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein

29 September 2017

1 reference

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Lipoxygenase mRNA silencing in erythroid differentiation: The 3'UTR regulatory complex controls 60S ribosomal subunit joining

29 September 2017

1 reference

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Regulation of tyrosine hydroxylase mRNA stability by protein-binding, pyrimidine-rich sequence in the 3'-untranslated region

29 September 2017

1 reference

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Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

p21(waf1) mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

Identification of a novel p53 functional domain that is necessary for mediating apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

p53-dependent elevation of p21Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

Posttranscriptional regulation of collagen alpha1(I) mRNA in hepatic stellate cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

The KH domain occurs in a diverse set of RNA-binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid.

29 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ778

Expression of alpha CP-4 inhibits cell cycle progression and suppresses tumorigenicity of lung cancer cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ778

Immunoprecipitation of mRNA-protein complexes.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ778

Poly (rC) binding protein 2 forms a ternary complex with the 5'-terminal sequences of poliovirus RNA and the viral 3CD proteinase.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017617

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20817677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ectopic p21(WAF1) expression induces differentiation-specific cell cycle changes in PC12 cells characteristic of nerve growth factor treatment

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20817677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKQ778

1 reference

journals/nar/ScoumanneCZC11

2042580

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

2042580

1 reference

1 reference

1 reference