Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression (Q28115890)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression (English)

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

Fos proto-oncogene, AP-1 transcription factor subunit

29 February 2020

main subject

1 reference

GOA release 2020-03-11

PTEN induced kinase 1

1 reference

GOA release 2020-03-11

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Rubén Gómez-Sánchez

1

1 reference

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29 February 2020

Matthew E Gegg

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

José Manuel Bravo-San Pedro

29 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

Alberto Alvarez-Barrientos

29 February 2020

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

José M. Fuentes

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Rosa-Ana González Polo

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

5

Lydia Alvarez-Erviti

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

11

Anthony H V Schapira

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Elisa Pizarro-Estrella

6

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Yolanda Gutiérrez-Martín

7

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

publication date

29 October 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

published in

Neurobiology of Disease

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

62

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

426-440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

29 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3898697/fullTextXML

inferred from PubMed Central ID database lookup

cites work

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

1 reference

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

20 March 2017

1 reference

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The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking

20 March 2017

1 reference

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Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

20 March 2017

1 reference

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Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

20 March 2017

1 reference

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p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

20 March 2017

1 reference

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

20 March 2017

1 reference

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PINK1 cleavage at position A103 by the mitochondrial protease PARL.

20 March 2017

1 reference

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

20 March 2017

1 reference

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

20 March 2017

1 reference

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The kinase domain of mitochondrial PINK1 faces the cytoplasm

20 March 2017

1 reference

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PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons

20 March 2017

1 reference

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

20 March 2017

1 reference

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G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

20 March 2017

1 reference

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Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

20 March 2017

1 reference

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

20 March 2017

1 reference

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

20 March 2017

1 reference

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Selective degradation of mitochondria by mitophagy

20 March 2017

1 reference

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20 March 2017

Mechanisms of mitophagy

1 reference

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Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

20 March 2017

1 reference

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A new mathematical model for relative quantification in real-time RT-PCR

20 March 2017

1 reference

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

20 March 2017

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Bioenergetic consequences of PINK1 mutations in Parkinson disease

20 March 2017

1 reference

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Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.

20 March 2017

1 reference

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Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

20 March 2017

1 reference

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c-fos regulates neuronal excitability and survival

20 March 2017

1 reference

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A guided tour into subcellular colocalization analysis in light microscopy

20 March 2017

1 reference

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

7 April 2017

1 reference

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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

7 April 2017

1 reference

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Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

7 April 2017

1 reference

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

7 April 2017

1 reference

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Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

7 April 2017

1 reference

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The PINK1/Parkin pathway regulates mitochondrial morphology

7 April 2017

1 reference

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

7 April 2017

1 reference

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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

7 April 2017

1 reference

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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

7 April 2017

1 reference

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PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

7 April 2017

1 reference

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The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease.

29 September 2017

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Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson's disease

29 September 2017

1 reference

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Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

29 September 2017

1 reference

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Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression.

29 September 2017

1 reference

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Effects of Lipofectamine 2000/siRNA complexes on autophagy in hepatoma cells

29 September 2017

1 reference

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Mechanisms of specificity in neuronal activity-regulated gene transcription

29 September 2017

1 reference

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The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease

29 September 2017

1 reference

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Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice

29 September 2017

1 reference

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FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress

29 September 2017

1 reference

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Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells

29 September 2017

1 reference

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Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

29 September 2017

1 reference

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PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

29 September 2017

1 reference

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FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

29 September 2017

1 reference

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Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells

29 September 2017

1 reference

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Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux

29 September 2017

1 reference

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Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin

29 September 2017

1 reference

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Multiple roles of calcium ions in the regulation of neurotransmitter release

29 September 2017

1 reference

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Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

29 September 2017

1 reference

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Characterization of PINK1 processing, stability, and subcellular localization

29 September 2017

1 reference

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Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain

29 September 2017

1 reference

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Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP.

29 September 2017

1 reference

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Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

29 September 2017

1 reference

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Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1.

29 September 2017

1 reference

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Inhibition of paraquat-induced autophagy accelerates the apoptotic cell death in neuroblastoma SH-SY5Y cells.

29 September 2017

1 reference

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Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.

29 September 2017

1 reference

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C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.

29 September 2017

1 reference

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Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

29 September 2017

1 reference

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Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations

29 September 2017

1 reference

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Idiopathic Parkinson's disease: a genetic and environmental model

29 September 2017

1 reference

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Genetic and environmental factors in Parkinson's disease.

29 September 2017

1 reference

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Calcium- and activity-dependent synaptic plasticity

29 September 2017

1 reference

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Respiratory uncoupling induces delta-aminolevulinate synthase expression through a nuclear respiratory factor-1-dependent mechanism in HeLa cells.

29 September 2017

1 reference

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Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk

29 September 2017

1 reference

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Mitochondrial participation in the intracellular Ca2+ network

29 September 2017

1 reference

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L-type voltage-sensitive Ca2+ channel activation regulates c-fos transcription at multiple levels

29 September 2017

1 reference

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The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway

29 September 2017

1 reference

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Regulation of mitochondrial permeability transition pore by PINK1.

2 June 2018

1 reference

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Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance

2 June 2018

1 reference

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Ca(2+) homeostasis, Ca(2+) signalling and somatodendritic vasopressin release in adult rat supraoptic nucleus neurones

2 June 2018

1 reference

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Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology.

2 June 2018

1 reference

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Mitochondrial inhibitors activate influx of external Ca(2+) in sea urchin sperm

2 June 2018

1 reference

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Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability

2 June 2018

1 reference

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Effects of the removal of extracellular Ca2+ on [Ca2+]i responses to FCCP and acetate in carotid body glomus cells of adult rabbits.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Dominant role of mitochondria in clearance of large Ca2+ loads from rat adrenal chromaffin cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Differential effects of 2-oxo acids on pyruvate utilization and fatty acid synthesis in rat brain

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Ca2+ homeostasis and exocytosis in carotid glomus cells: role of mitochondria.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Impaired presynaptic cytosolic and mitochondrial calcium dynamics in aged compared to young adult hippocampal CA1 synapses ameliorated by calcium chelation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Carbonyl cyanide m-chlorophenylhydrazone induced calcium signaling and activation of plasma membrane H(+)-ATPase in the yeast Saccharomyces cerevisiae.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

CCCP enhances catecholamine release from the perfused rat adrenal medulla

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Suppression of calcium release from inositol 1,4,5-trisphosphate-sensitive stores mediates the anti-apoptotic function of nuclear factor-kappaB.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Early c-Fos induction after cerebral ischemia: a possible neuroprotective role

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Effects of mitochondrial uncouplers on intracellular calcium, pH and membrane potential in rat carotid body type I cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3898697

Clean Western blots of membrane proteins after yeast heterologous expression following a shortened version of the method of Perini et al

27 November 2018

1 reference

12 December 2020

Excitotoxicity and nitric oxide in Parkinson's disease pathogenesis

1 reference

12 December 2020

L-type Ca(2+) channel activation regulates induction of c-fos transcription by hypoxia

1 reference

12 December 2020

Does the calcium binding protein calretinin protect dopaminergic neurons against degeneration in Parkinson's disease?

1 reference

12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

12 December 2020

Transient increase in Ca2+ influx in Saccharomyces cerevisiae in response to glucose: effects of intracellular acidification and cAMP levels

1 reference

12 December 2020

Ca2+ influx through both L- and N-type Ca2+ channels increases c-fos expression by electrical stimulation of sympathetic neurons

1 reference

12 December 2020

10.1016/J.NBD.2013.10.021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24184327%20AND%20SRC:MED&resulttype=core&format=json