Development of thymic Foxp3(+) regulatory T cells: TGF-β matters (Q28080745)

Crossref

Joanne E. Konkel

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

April 2015

1 reference

European Journal of Immunology

published in

1 reference

volume

45

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issue

4

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page(s)

958-65

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T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

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Smad4 and FAST-1 in the assembly of activin-responsive factor

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Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

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Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)

20 March 2017

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

7 April 2017

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Epigenetic control of thymic Treg-cell development

7 April 2017

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Thymocyte apoptosis drives the intrathymic generation of regulatory T cells

29 September 2017

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TGF-β activation and function in immunity

29 September 2017

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Strength of TCR signal from self-peptide modulates autoreactive thymocyte deletion and Foxp3(+) Treg-cell formation

29 September 2017

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Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals

29 September 2017

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The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development

29 September 2017

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Development and maintenance of regulatory T cells

29 September 2017

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A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self.

29 September 2017

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Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut.

29 September 2017

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Selection of regulatory T cells in the thymus

29 September 2017

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Selection of self-reactive T cells in the thymus

29 September 2017

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Regulatory T cell lineage commitment in the thymus

29 September 2017

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T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse

29 September 2017

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Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3.

29 September 2017

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Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development

29 September 2017

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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

29 September 2017

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Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome

29 September 2017

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Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.

29 September 2017

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Intraclonal competition limits the fate determination of regulatory T cells in the thymus

29 September 2017

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Transcriptional and translational regulation of TGF-beta production in response to apoptotic cells

29 September 2017

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Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

29 September 2017

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A two-step process for thymic regulatory T cell development.

29 September 2017

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Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

29 September 2017

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Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells

29 September 2017

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Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells

29 September 2017

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Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

29 September 2017

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Developmental regulation of Foxp3 expression during ontogeny.

29 September 2017

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CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

29 September 2017

1 reference

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Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.

29 September 2017

1 reference

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Requirement for transforming growth factor beta1 in controlling T cell apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428761

TGF-beta influences the life and death decisions of T lymphocytes

29 September 2017

1 reference

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Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

29 September 2017

1 reference

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Control of the development of CD8αα+ intestinal intraepithelial lymphocytes by TGF-β.

29 September 2017

1 reference

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Critical role of IL-2 and TGF-beta in generation, function and stabilization of Foxp3+CD4+ Treg.

27 November 2018

1 reference

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The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

27 November 2018

1 reference

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In vivo-generated antigen-specific regulatory T cells treat autoimmunity without compromising antibacterial immune response

27 November 2018

1 reference

12 December 2020

Inducing and expanding regulatory T cell populations by foreign antigen

1 reference

12 December 2020

Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cells

1 reference

12 December 2020

A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

1 reference

12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

12 December 2020

TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu

1 reference

12 December 2020

Origin of regulatory T cells with known specificity for antigen

1 reference

12 December 2020

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

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12 December 2020

T-cell apoptosis detected in situ during positive and negative selection in the thymus

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12 December 2020

Identifiers

DOI

10.1002/EJI.201444999

1 reference

release_gcdabqrkpjh5zbiej4g3dbghx4

1681433

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/gcdabqrkpjh5zbiej4g3dbghx4

24 November 2022

mapped directly with Wikidata item

1681433

1 reference

1 reference

1 reference