The diagnostic and prognostic value of systems biology research in major traumatic and thermal injury: a review (Q28079517)

title

The diagnostic and prognostic value of systems biology research in major traumatic and thermal injury: a review (English)

1 reference

1 reference

Peter Hampson

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27672669%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

1 reference

21 September 2016

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27672669%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27672669%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

33

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27672669%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 4.0 International

1 June 2020

copyright license

start time

10 January 2020

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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29 September 2017

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Temporal Patterns of Circulating Inflammation Biomarker Networks Differentiate Susceptibility to Nosocomial Infection Following Blunt Trauma in Humans.

29 September 2017

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Genomic responses in mouse models greatly mimic human inflammatory diseases

29 September 2017

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29 September 2017

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29 September 2017

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Elevated levels of plasma mitochondrial DNA DAMPs are linked to clinical outcome in severely injured human subjects

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Metabolomics--a novel window into inflammatory disease.

29 September 2017

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Inhalation injury severity and systemic immune perturbations in burned adults

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Proteomics improves the prediction of burns mortality: results from regression spline modeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Targeted metabolomics for discrimination of systemic inflammatory disorders in critically ill patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Early interleukin-6 and slope of monocyte human leukocyte antigen-DR: a powerful association to predict the development of sepsis after major trauma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern

29 September 2017

1 reference

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A genomic storm in critically injured humans

29 September 2017

1 reference

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Concentrations of cytokines IL-6 and IL-10 in plasma of burn patients: their relationship to sepsis and outcome

29 September 2017

1 reference

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Early pulmonary immune hyporesponsiveness is associated with mortality after burn and smoke inhalation injury

29 September 2017

1 reference

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29 September 2017

1 reference

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Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Increases in mortality, length of stay, and cost associated with hospital-acquired infections in trauma patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Human traumatic brain injury alters plasma microRNA levels.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Early elevation in random plasma IL-6 after severe injury is associated with development of organ failure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Serum IL-6: a candidate biomarker for intracranial pressure elevation following isolated traumatic brain injury.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

IL-6 predicts organ dysfunction and mortality in patients with multiple injuries.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Early cytokine production risk stratifies trauma patients for multiple organ failure.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

A genomic score prognostic of outcome in trauma patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Are serum cytokines early predictors for the outcome of burn patients with inhalation injuries who do not survive?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Multiple organ failure after trauma affects even long-term survival and functional status

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Trauma: the role of the innate immune system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Trauma patient hospital-associated infections: risks and outcomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Epidemiology of sepsis in patients with traumatic injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Time course of pro- and anti-inflammatory cytokine levels in patients with burns--prognostic value of interleukin-10.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Stimulation of inflammatory markers after blunt trauma

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Risk factors for nosocomial infection in trauma patients

2 June 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

Genomic responses to inflammation in mouse models mimic humans: we concur, apples to oranges comparisons won't do.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

It's all in the genes: moving toward precision medicine in critical illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

Altered expression levels of miRNAs in serum as sensitive biomarkers for early diagnosis of traumatic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

Interleukin-10 is an independent biomarker of severe traumatic brain injury prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

Investigation of the course of proinflammatory and anti-inflammatory cytokines after burn sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

Plasma metabolite profiles following trauma-hemorrhage: effect of posttreatment with resveratrol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

Metabolic phenotyping of traumatized patients reveals a susceptibility to sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

Characterization of circulating monocytes expressing HLA-DR or CD71 and related soluble factors for 2 weeks after severe, non-thermal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41038-016-0059-3

Early changes in frequency of peripheral blood lymphocyte subpopulations in severe traumatic brain-injured patients.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

Early versus late onset of multiple organ failure is associated with differing patterns of plasma cytokine biomarker expression and outcome after severe trauma.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030723

[Changes in human leukocyte antigen-DR expression on monocytes and its value of prediction on infection complication in trauma patients]

27 November 2018

1 reference

12 December 2020

[Changes in serum contents of interleukin-6 and interleukin-10 and their relation with occurrence of sepsis and prognosis of severely burned patients]

1 reference

12 December 2020

Neutrophil chemiluminescence in burned patients

1 reference

12 December 2020

A sequential, prospective analysis of immunologic abnormalities and infection following severe thermal injury

1 reference

12 December 2020

Decreased monocyte human leukocyte antigen-DR expression after severe burn injury: Correlation with severity and secondary septic shock

1 reference

12 December 2020

Metabolomics classifies phase of care and identifies risk for mortality in a porcine model of multiple injuries and hemorrhagic shock

1 reference

12 December 2020

Increased levels of interleukin-6, -8 and -10 are associated with fatal outcome following severe traumatic brain injury

1 reference

12 December 2020

10.1186/S41038-016-0059-3

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27672669%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

1013688578

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27672669%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

27672669

2 references