Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock. (Q35497590)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Henry V. Baker

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Scott C Brakenridge

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

14

Lyle L Moldawer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Christiaan Leeuwenburgh

11

object named as

Christiaan Leeuwenburgh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

16

Philip A Efron

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Erin L Vanzant

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Rachael E Hilton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Cecilia M Lopez

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jianyi Zhang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Ricardo F Ungaro

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Lori F Gentile

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Benjamin E Szpila

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Ronald V Maier

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Joseph Cuschieri

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Frederick A Moore

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Inflammation and Host Response to Injury Investigators

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

publication date

4 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

77

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/s13054-015-0788-x

5 March 2020

exact match

0 references

cites work

Persistent inflammation and T cell exhaustion in severe sepsis in the elderly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Benchmarking outcomes in the critically injured burn patient

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Protective immunity and defects in the neonatal and elderly immune response to sepsis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

A better understanding of why murine models of trauma do not recapitulate the human syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Aged mice are unable to mount an effective myeloid response to sepsis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Toll like receptor signaling in "inflammaging": microRNA as new players.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Genomic responses in mouse models poorly mimic human inflammatory diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

A genomic storm in critically injured humans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Human transcriptome array for high-throughput clinical studies.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Models of lower extremity damage in mice: time course of organ damage and immune response

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Attenuated response of aged mice to respiratory Francisella novicida is characterized by reduced cell death and absence of subsequent hypercytokinemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

The effects of aging on pulmonary oxidative damage, protein nitration, and extracellular superoxide dismutase down-regulation during systemic inflammation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Inflammation and the host response to injury, a Large-Scale Collaborative Project: patient-oriented research core standard operating procedures for clinical care IX. Definitions for complications of clinical care of critically injured patients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

A genomic score prognostic of outcome in trauma patients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Effects of aging on the immunopathologic response to sepsis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

30 years of polytrauma care: An analysis of the change in strategies and results of 4849 cases treated at a single institution

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Sepsis: time to reconsider the concept

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Aging of the immune system: how much can the adaptive immune system adapt?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Application of genome-wide expression analysis to human health and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Application of z-score transformation to Affymetrix data

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Sepsis syndromes: understanding the role of innate and acquired immunity.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Outcome after hemorrhagic shock in trauma patients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

TRISS methodology in trauma: the need for alternatives

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Multiple organ failure, multiple organ dysfunction syndrome, and systemic inflammatory response syndrome. Why no magic bullets?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Epidemiology of sepsis syndrome in 8 academic medical centers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Mortality in trauma patients: the interaction between host factors and severity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Influence of sex and age on morphological organ damage after hemorrhagic shock.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Geriatric outcomes are improved by a geriatric trauma consultation service

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Preventing death and disability through the timely provision of prehospital trauma care

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Inflammation and the Host Response to Injury, a Large-Scale Collaborative Project: patient-oriented research core--standard operating procedures for clinical care. II. Guidelines for prevention, diagnosis and treatment of ventilator-associated pneum

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Influence of gender and age on T-cell responses in a murine model of trauma-hemorrhage: differences between circulating and tissue-fixed cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Are the immune responses different in middle-aged and young mice following bone fracture, tissue trauma and hemorrhage?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Posttraumatic complications and changes in blood lymphocyte populations after multiple trauma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404112

Aging and Innate Immunity

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS13054-015-0788-X

Whole blood and leukocyte RNA isolation for gene expression analyses

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS13054-015-0788-X

Early predictors of postinjury multiple organ failure

21 January 2018

1 reference

12 December 2020

Changes in blood lymphocyte populations after multiple trauma: association with posttraumatic complications

1 reference

12 December 2020

Sepsis, Systemic Inflammatory Response Syndrome, Multiple Organ Dysfunction Syndrome, and Multiple Organ Failure: Are Trauma Surgeons Lumpers or Splitters?

1 reference

12 December 2020

Postinjury multiple organ failure: a bimodal phenomenon

1 reference

12 December 2020

Improved survival of critically ill trauma patients treated with recombinant human erythropoietin

1 reference

12 December 2020

10.1186/S13054-015-0788-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880307%20AND%20SRC:MED&resulttype=core&format=json