A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging? (Q28078724)

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English	A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?	scientific article

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scholarly article

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Europe PubMed Central

A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging? (English)

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quality control

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neurodegeneration

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based on heuristic

inferred from title

1

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2 June 2020

5

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2 June 2020

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Ayeman Amanullah

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2 June 2020

Arun Upadhyay

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2 June 2020

Ribhav Mishra

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2 June 2020

Amit Mishra

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2 June 2020

language of work or name

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publication date

4 October 2016

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Frontiers in Molecular Neuroscience

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2 June 2020

93

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Europe PubMed Central

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2 June 2020

CHIP: A new modulator of human malignant disorders

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Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases

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Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease

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HECT and RING finger families of E3 ubiquitin ligases at a glance

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Quality control and fate determination of Hsp90 client proteins

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Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP

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CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response

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CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation

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20 March 2017

Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes

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20 March 2017

Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases

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Akt and CHIP coregulate tau degradation through coordinated interactions

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Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling

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Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology

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CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation

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Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

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Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin

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20 March 2017

Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase

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20 March 2017

The Jalview Java alignment editor

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20 March 2017

Structural insights into the U-box, a domain associated with multi-ubiquitination

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20 March 2017

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

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20 March 2017

U box proteins as a new family of ubiquitin-protein ligases

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20 March 2017

Mechanisms underlying ubiquitination

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20 March 2017

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

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20 March 2017

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

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Ubiquitin-dependent protein degradation

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20 March 2017

Hsp70 and Hsp90 oppositely regulate TGF-β signaling through CHIP/Stub1

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20 March 2017

Chaperone-assisted selective autophagy is essential for muscle maintenance

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20 March 2017

CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

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20 March 2017

ErbB2 degradation mediated by the co-chaperone protein CHIP

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20 March 2017

Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX

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Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

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CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

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Biochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP

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CHIP has a protective role against oxidative stress-induced cell death through specific regulation of endonuclease G

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20 March 2017

Chaperone-dependent E3 ligase CHIP ubiquitinates and mediates proteasomal degradation of soluble guanylyl cyclase

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CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70

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Regulation of the cytoplasmic quality control protein degradation pathway by BAG2

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CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

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Identification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxia

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STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy

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Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

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29 September 2017

The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5.

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29 September 2017

CHIP Knockdown Reduced Heat Shock Response and Protein Quality Control Capacity in Lens Epithelial Cells.

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29 September 2017

Phosphorylation of CHIP at Ser20 by Cdk5 promotes tAIF-mediated neuronal death

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29 September 2017

CHIP: a co-chaperone for degradation by the proteasome

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29 September 2017

A CHIPotle in physiology and disease.

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29 September 2017

Trehalose improves human fibroblast deficits in a new CHIP-mutation related ataxia.

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29 September 2017

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29 September 2017

Ubiquitination of inositol-requiring enzyme 1 (IRE1) by the E3 ligase CHIP mediates the IRE1/TRAF2/JNK pathway

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29 September 2017

Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.

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29 September 2017

The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

The ubiquitin ligase CHIP prevents SirT6 degradation through noncanonical ubiquitination

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29 September 2017

USP47 and C terminus of Hsp70-interacting protein (CHIP) antagonistically regulate katanin-p60-mediated axonal growth

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29 September 2017

Inhibition of histone deacetylase activity suppresses IFN-γ induction of tripartite motif 22 via CHIP-mediated proteasomal degradation of IRF-1.

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29 September 2017

Ube2W conjugates ubiquitin to α-amino groups of protein N-termini

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29 September 2017

STUB1 is essential for T-cell activation by ubiquitinating CARMA1.

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29 September 2017

Androgen receptor degradation by the E3 ligase CHIP modulates mitotic arrest in prostate cancer cells

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29 September 2017

Chaperones in autophagy

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29 September 2017

Misfolded proteins recognition strategies of E3 ubiquitin ligases and neurodegenerative diseases

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29 September 2017

Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.

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29 September 2017

Degradation of tau protein by autophagy and proteasomal pathways

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29 September 2017

Haploinsufficiency of the E3 ubiquitin ligase C-terminus of heat shock cognate 70 interacting protein (CHIP) produces specific behavioral impairments

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Neurofilament Phosphorylation during Development and Disease: Which Came First, the Phosphorylation or the Accumulation?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Carboxy terminus of heat shock protein (HSP) 70-interacting protein (CHIP) inhibits HSP70 in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Ubc13 and COOH terminus of Hsp70-interacting protein (CHIP) are required for growth hormone receptor endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Multisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78- and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKC{zeta}.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

C terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Ubiquitin ligase CHIP induces TRAF2 proteasomal degradation and NF-κB inactivation to regulate breast cancer cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Malin and laforin are essential components of a protein complex that protects cells from thermal stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

E2 conjugating enzyme selectivity and requirements for function of the E3 ubiquitin ligase CHIP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP and gp78-mediated ubiquitination of CYP3A4: Implications for the pharmacology of anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Redox regulation of the stability of the SUMO protease SENP3 via interactions with CHIP and Hsp90.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Bag1 directly routes immature BCR-ABL for proteasomal degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Chaperone-assisted degradation: multiple paths to destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Identification of residues on Hsp70 and Hsp90 ubiquitinated by the cochaperone CHIP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Co-chaperone CHIP stabilizes aggregate-prone malin, a ubiquitin ligase mutated in Lafora disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Therapeutic strategies within the ubiquitin proteasome system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Regulation of LRRK2 stability by the E3 ubiquitin ligase CHIP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP functions an E3 ubiquitin ligase of Runx1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Chaperone signalling complexes in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP represses myocardin-induced smooth muscle cell differentiation via ubiquitin-mediated proteasomal degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP targets toxic alpha-Synuclein oligomers for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Differential ubiquitination of Smad1 mediated by CHIP: implications in the regulation of the bone morphogenetic protein signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

The co-chaperone CHIP is induced in various stresses and confers protection to cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Curcumin-induced degradation of ErbB2: A role for the E3 ubiquitin ligase CHIP and the Michael reaction acceptor activity of curcumin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Carboxyl terminus of hsc70-interacting protein (CHIP) can remodel mature aryl hydrocarbon receptor (AhR) complexes and mediate ubiquitination of both the AhR and the 90 kDa heat-shock protein (hsp90) in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Brain CHIP: removing the culprits in neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Co-chaperone CHIP promotes aggregation of ataxin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Ubiquitination and proteasome-dependent degradation of human eukaryotic translation initiation factor 4E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Protein ubiquitination: CHIPping away the symmetry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Alternative effects of the ubiquitin-proteasome pathway on glucocorticoid receptor down-regulation and transactivation are mediated by CHIP, an E3 ligase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Tau, tangles, and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP: a link between the chaperone and proteasome systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Getting into position: the catalytic mechanisms of protein ubiquitylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP activates HSF1 and confers protection against apoptosis and cellular stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP: a quality-control E3 ligase collaborating with molecular chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

PTEN regulation of neural development and CNS stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Chaperoning signaling pathways: molecular chaperones as stress-sensing 'heat shock' proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Cell death mechanisms in neurodegeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

From the cradle to the grave: molecular chaperones that may choose between folding and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

Autophagy and other vacuolar protein degradation mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

29 September 2017

CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: role of the co-chaperone carboxyl heat shock protein 70-interacting protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

2 June 2018

CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Protein quality control: U-box-containing E3 ubiquitin ligases join the fold

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Mineralocorticoid receptor degradation is promoted by Hsp90 inhibition and the ubiquitin-protein ligase CHIP.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Insights into the conformational dynamics of the E3 ubiquitin ligase CHIP in complex with chaperones and E2 enzymes.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Tid1, CHIP and ErbB2 interactions and their prognostic implications for breast cancer patients.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

C-terminus of Hsc70-interacting protein regulates C-terminal binding protein 2 and the expression of its target genes

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

CHIPping away at base excision repair.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

UBXN2A regulates nicotinic receptor degradation by modulating the E3 ligase activity of CHIP.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Carboxyl-terminus of Hsc70 interacting protein mediates 2,5-hexanedione-induced neurofilament medium chain degradation.

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Metastatic lymph node CHIP expression is a potential prognostic marker for resected esophageal squamous cell carcinoma patients

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

The U box is a modified RING finger — a common domain in ubiquitination

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

CHIP promotes the degradation of mutant SOD1 by reducing its interaction with VCP and S6/S6′ subunits of 26S proteasome

1 reference

https://api.crossref.org/works/10.3389%2FFNMOL.2016.00093

21 January 2018

Genetic screening for mutations in the chip gene in intracranial aneurysm patients of Chinese Han nationality.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5047891

27 November 2018

Targeting the ubiquitin-proteasome system for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/27757073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta, tau and ApoE4 in Alzheimer's disease: the axonal connection

1 reference

https://pubmed.ncbi.nlm.nih.gov/27757073

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FNMOL.2016.00093

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27757073%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

release_nqv7gl5sprgtnlhgem7bmyhzlu

1 reference

https://api.fatcat.wiki/v0/release/nqv7gl5sprgtnlhgem7bmyhzlu

24 November 2022

based on heuristic

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27757073%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27757073%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

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