Epigenetic Therapeutics: A New Weapon in the War Against Cancer (Q28072370)

Crossref

Anup R. Sharma

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

2016

1 reference

Annual Review of Medicine

published in

1 reference

volume

67

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page(s)

73-89

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The emerging molecular machinery and therapeutic targets of metastasis

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

20 March 2017

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An operational definition of epigenetics

20 March 2017

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Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

20 March 2017

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Wnt/beta-catenin signaling in development and disease

20 March 2017

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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

20 March 2017

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The complex language of chromatin regulation during transcription

20 March 2017

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Comprehensive genomic characterization of head and neck squamous cell carcinomas

20 March 2017

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ARID1A mutations in cancer: another epigenetic tumor suppressor?

20 March 2017

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Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

20 March 2017

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Carboplatin and Paclitaxel in combination with either vorinostat or placebo for first-line therapy of advanced non-small-cell lung cancer

20 March 2017

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The epigenomics of cancer

20 March 2017

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5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal

20 March 2017

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Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

20 March 2017

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IDH mutation impairs histone demethylation and results in a block to cell differentiation

20 March 2017

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

7 April 2017

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EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

7 April 2017

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Cancer epigenetics: from mechanism to therapy

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7 April 2017

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7 April 2017

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Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer

7 April 2017

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7 April 2017

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Genetic basis for clinical response to CTLA-4 blockade in melanoma

7 April 2017

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Epigenetic regulation by long noncoding RNAs

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

7 April 2017

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Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

7 April 2017

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DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

29 September 2017

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29 September 2017

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Oxygen concentration controls epigenetic effects in models of familial paraganglioma

29 September 2017

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Clinical cancer advances 2015: Annual report on progress against cancer from the American Society of Clinical Oncology

29 September 2017

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Notes on the role of dynamic DNA methylation in mammalian development

29 September 2017

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Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial

29 September 2017

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Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights

29 September 2017

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DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos.

29 September 2017

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Erasers of histone acetylation: the histone deacetylase enzymes

29 September 2017

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Histone H3 mutations in pediatric brain tumors

29 September 2017

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Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905.

29 September 2017

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Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers.

29 September 2017

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Harnessing the potential of epigenetic therapy to target solid tumors.

29 September 2017

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A new world of Polycombs: unexpected partnerships and emerging functions

29 September 2017

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Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine

29 September 2017

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DNMT1-interacting RNAs block gene-specific DNA methylation

29 September 2017

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The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes

29 September 2017

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TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

29 September 2017

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Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal a

29 September 2017

1 reference

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Cancer genome-sequencing study design

29 September 2017

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The future of epigenetic therapy in solid tumours--lessons from the past.

29 September 2017

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Interplay between the cancer genome and epigenome

29 September 2017

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Lessons from the cancer genome

29 September 2017

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Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas

29 September 2017

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An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy

29 September 2017

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HDAC inhibitors: roles of DNA damage and repair

29 September 2017

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A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

29 September 2017

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Cancer genetics and epigenetics: two sides of the same coin?

29 September 2017

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Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer

29 September 2017

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A complex Polycomb issue: the two faces of EZH2 in cancer

29 September 2017

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Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

29 September 2017

1 reference

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Cancer epigenomics: beyond genomics

29 September 2017

1 reference

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Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

29 September 2017

1 reference

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Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes

29 September 2017

1 reference

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Phase 1b-2a study to reverse platinum resistance through use of a hypomethylating agent, azacitidine, in patients with platinum-resistant or platinum-refractory epithelial ovarian cancer

29 September 2017

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Epigenetic modifications as therapeutic targets

29 September 2017

1 reference

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A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

29 September 2017

1 reference

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S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth

29 September 2017

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Polycomb group protein-mediated repression of transcription

29 September 2017

1 reference

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DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

29 September 2017

1 reference

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Polycomb group proteins: navigators of lineage pathways led astray in cancer

29 September 2017

1 reference

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Using genetic diagnosis to determine individual therapeutic utility

29 September 2017

1 reference

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Demethylating agents in myeloid malignancies

29 September 2017

1 reference

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Histone deacetylase regulation of immune gene expression in tumor cells

29 September 2017

1 reference

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Dynamics and interplay of nuclear architecture, genome organization, and gene expression

29 September 2017

1 reference

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Methylation inhibitor therapy in the treatment of myelodysplastic syndrome

29 September 2017

1 reference

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FDA drug approval summary: azacitidine (5-azacytidine, Vidaza) for injectable suspension

29 September 2017

1 reference

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Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine

29 September 2017

1 reference

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Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

29 September 2017

1 reference

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DNA methylation, methyltransferases, and cancer

29 September 2017

1 reference

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DNA methylation inhibitors in the treatment of leukemias, myelodysplastic syndromes and hemoglobinopathies: clinical results and possible mechanisms of action

29 September 2017

1 reference

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Cellular differentiation, cytidine analogs and DNA methylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4937439

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.

2 June 2018

1 reference

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Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes.

27 November 2018

1 reference

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Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome.

27 November 2018

1 reference

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DNA methylation in the treatment of hematologic malignancies.

27 November 2018

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10.1146/ANNUREV-MED-111314-035900

27 November 2018

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4215490

OpenCitations bibliographic resource ID

4215490

1 reference