Molecular Targets Underlying the Anticancer Effects of Quercetin: An Update (Q28068006)

Kalyan Nagulapalli Venkata

6

0 references

Fazlullah Khan

Fazlullah Khan

1

0 references

Kamal Niaz

Kamal Niaz

2

0 references

Mohammad Abdollahi

Mohammad Abdollahi

5

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author name string

Faheem Maqbool

3

1 reference

Fatima Ismail Hassan

4

1 reference

Seyed Nabavi

7

1 reference

Anupam Bishayee

8

1 reference

language of work or name

1 reference

29 August 2016

8 references

3 April 2019

30 June 2019

20 August 2019

17 September 2019

14 September 2020

16 July 2021

19 January 2024

7 references

3 April 2019

30 June 2019

20 August 2019

17 September 2019

14 September 2020

16 July 2021

19 January 2024

8

1 reference

issue

9

1 reference

Creative Commons Attribution

page(s)

529

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copyright license

7 references

3 April 2019

30 June 2019

20 August 2019

17 September 2019

14 September 2020

16 July 2021

19 January 2024

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on focus list of Wikimedia project

ScienceSource

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cites work

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The stimulation of cell proliferation by quercetin is mediated by the estrogen receptor.

29 September 2017

1 reference

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Dietary flavonoids and cancer risk: evidence from human population studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Flavonoids and the brain: interactions at the blood-brain barrier and their physiological effects on the central nervous system

29 September 2017

1 reference

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Anthocyanins and other flavonoids.

29 September 2017

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Bioactive compounds in nutrition and health-research methodologies for establishing biological function: the antioxidant and anti-inflammatory effects of flavonoids on atherosclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Calpha

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Quercetin suppresses proinflammatory cytokines production through MAP kinases andNF-kappaB pathway in lipopolysaccharide-stimulated macrophage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Inhibition of carcinogenesis by dietary polyphenolic compounds

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Quercetin inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Accumulation of quercetin conjugates in blood plasma after the short-term ingestion of onion by women

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Antioxidants and cancer, part 3: quercetin

29 September 2017

1 reference

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Quercetin and anti-CD95(Fas/Apo1) enhance apoptosis in HPB-ALL cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Involvement of transcription factor Sp1 in quercetin-mediated inhibitory effect on the androgen receptor in human prostate cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Dietary antioxidants and lung cancer risk: a case-control study in Uruguay.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Differential modulation of neuron survival during development by nerve growth factor binding to the p75 neurotrophin receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and ornithine decarboxylase activity by quercetin: possible involvement of lipoxygenase inhibition.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships

2 June 2018

1 reference

Protection of flavonoids against lipid peroxidation: the structure activity relationship revisited

21 January 2018

1 reference

Differentiation induced by Achyrocline satureioides (Lam) infusion in PC12 cells

21 January 2018

1 reference

Cell culture protection and in vivo neuroprotective capacity of flavonoids

21 January 2018

1 reference

Protective effect of quercetin against ICV colchicine-induced cognitive dysfunctions and oxidative damage in rats

21 January 2018

1 reference

Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice

21 January 2018

1 reference

Quercetin reverses D-galactose induced neurotoxicity in mouse brain.

21 January 2018

1 reference

Route of administration determines the anxiolytic activity of the flavonols kaempferol, quercetin and myricetin--are they prodrugs?

21 January 2018

1 reference

Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats.

21 January 2018

1 reference

Quercetin in an animal model of spinal cord compression injury: correlation of treatment duration with recovery of motor function

21 January 2018

1 reference

Oxidative damage shifts from lipid peroxidation to thiol arylation by catechol-containing antioxidants

21 January 2018

1 reference

STAT1 phosphorylation and cleavage is regulated by the histamine (H4) receptor in human atopic and non-atopic lymphocytes

21 January 2018

1 reference

Quercetin, a flavonoid phytoestrogen, ameliorates experimental allergic encephalomyelitis by blocking IL-12 signaling through JAK-STAT pathway in T lymphocyte

21 January 2018

1 reference

Quercetin, but not its metabolite quercetin-3-glucuronide, exerts prophylactic immunostimulatory activity and therapeutic antiinflammatory effects on lipopolysaccharide-treated mouse peritoneal macrophages ex vivo.

21 January 2018

1 reference

The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition

21 January 2018

1 reference

Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice.

21 January 2018

1 reference

Akt is a direct target for myricetin to inhibit cell transformation.

21 January 2018

1 reference

Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells.

21 January 2018

1 reference

Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha- RAS -transformed human colon cells

21 January 2018

1 reference

Quercetin abrogates taxol-mediated signaling by inhibiting multiple kinases

21 January 2018

1 reference

The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells

21 January 2018

1 reference

Flavonol and flavone intake and the risk of cancer in male smokers (Finland).

21 January 2018

1 reference

CHIH-DFT determination of the molecular structure, infrared and ultraviolet spectra of the flavonoid quercetin

21 January 2018

1 reference

Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

The antiproliferative effect of Quercetin in cancer cells is mediated via inhibition of the PI3K-Akt/PKB pathway.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Flavonoid quercetin, but not apigenin or luteolin, induced apoptosis in human myeloid leukemia cells and their resistant variants.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Tissue distribution of quercetin in rats and pigs.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Unique uptake and transport of isoflavone aglycones by human intestinal caco-2 cells: comparison of isoflavonoids and flavonoids.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5037516

Quercetin enhances CD95- and TRAIL-induced apoptosis in leukemia cell lines

27 November 2018

1 reference

Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands

21 January 2018

1 reference

12 December 2020

Antioxidative and prooxidative effects of quercetin on A549 cells

1 reference

12 December 2020

Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential

1 reference

12 December 2020

Solophenols B-D and solomonin: new prenylated polyphenols isolated from propolis collected from the Solomon Islands and their antibacterial activity

1 reference

12 December 2020

A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer

1 reference

12 December 2020

Inhibition of 7,12-dimethylbenz(a)anthracene- and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin

1 reference

12 December 2020

[Studies on flavonoid constituents isolated from the leaves of Glycyrrhiza uralensis Fisch]

1 reference

12 December 2020

Inhibitory action of quercetin on xanthine oxidase and xanthine dehydrogenase activity

1 reference

12 December 2020

Comparative effects of flavonoids and model inducers on drug-metabolizing enzymes in rat liver

1 reference

12 December 2020

The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man

1 reference

12 December 2020

Flavones and flavonols at dietary levels inhibit a transformation of aryl hydrocarbon receptor induced by dioxin

1 reference

12 December 2020

Isolation of quercetin 3,7,3′,4′-tetrasulphate fromFlaveria bidentis L. Otto Kuntze

1 reference

12 December 2020