A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway (Q27936432)

Ste5p YDR103W

1 reference

G protein subunit beta YOR212W

1 reference

Cyclin CLN2 YPL256C

1 reference

author name string

Shelly C Strickfaden

1

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Matthew J Winters

2

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Giora Ben-Ari

3

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Rachel E Lamson

4

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Mike Tyers

5

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Peter M Pryciak

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.

6

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language of work or name

English

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publication date

9 February 2007

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1 reference

1 December 2016

128

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page(s)

519-31

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issue

3

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cites work

1 reference

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Cdk1-dependent regulation of the mitotic inhibitor Wee1.

20 March 2017

1 reference

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Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20.

20 March 2017

1 reference

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MAP kinase dynamics in response to pheromones in budding yeast

20 March 2017

1 reference

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Accurate quantitation of protein expression and site-specific phosphorylation

20 March 2017

1 reference

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Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p

20 March 2017

1 reference

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Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway

20 March 2017

1 reference

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Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1.

20 March 2017

1 reference

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Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Genetic control of the cell division cycle in yeast

20 March 2017

1 reference

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Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity.

7 April 2017

1 reference

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Interlinked fast and slow positive feedback loops drive reliable cell decisions

29 September 2017

1 reference

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Regulated cell-to-cell variation in a cell-fate decision system

29 September 2017

1 reference

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Regulation of G protein-initiated signal transduction in yeast: paradigms and principles

29 September 2017

1 reference

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Cycling through development in Drosophila and other metazoa

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Pheromone-dependent G1 cell cycle arrest requires Far1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Cln3-associated kinase activity in Saccharomyces cerevisiae is regulated by the mating factor pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

FAR1 is required for posttranscriptional regulation of CLN2 gene expression in response to mating pheromone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

G1 cyclins CLN1 and CLN2 repress the mating factor response pathway at Start in the yeast cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

FAR1 and the G1 phase specificity of cell cycle arrest by mating factor in Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Phosphorylation of FAR1 in response to alpha-factor: a possible requirement for cell-cycle arrest

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Functional binding between Gbeta and the LIM domain of Ste5 is required to activate the MEKK Ste11.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Overexpression of the G1-cyclin gene CLN2 represses the mating pathway in Saccharomyces cerevisiae at the level of the MEKK Ste11.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

A Membrane Binding Domain in the Ste5 Scaffold Synergizes with Gβγ Binding to Control Localization and Signaling in Pheromone Response

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Cyclin-dependent kinases regulate the antiproliferative function of Smads.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Improved flow cytometric analysis of the budding yeast cell cycle.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

MAPK specificity in the yeast pheromone response independent of transcriptional activation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Cyclin-specific START events and the G1-phase specificity of arrest by mating factor in budding yeast.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

Negative regulation of FAR1 at the Start of the yeast cell cycle.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847584

The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5

27 November 2018

1 reference

12 December 2020

Potential regulation of Ste20 function by the Cln1-Cdc28 and Cln2-Cdc28 cyclin-dependent protein kinases

1 reference

12 December 2020

Cell Cycle- and Cln2p-Cdc28p-dependent Phosphorylation of the Yeast Ste20p Protein Kinase

1 reference

12 December 2020

Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade

1 reference

12 December 2020

1 reference

12 December 2020

Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo

1 reference

12 December 2020

10.1016/J.CELL.2006.12.032

Identifiers

DOI

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4570287

4570287

1 reference

1 reference

1 reference