Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans (Q27935236)

GOA release 2020-03-11

transferase activity

1 reference

Ribosome biogenesis protein TSR3 YOR006C

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Peter Kötter

6

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Karl-Dieter Entian

9

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Jan Philip Wurm

2

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Jens Wöhnert

8

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Denys Pogoryelov

5

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author name string

Britta Meyer

1

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Sunny Sharma

3

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Carina Immer

4

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Denis L J Lafontaine

The diphthamide modification pathway from Saccharomyces cerevisiae--revisited

7

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language of work or name

English

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publication date

19 May 2016

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published in

Nucleic Acids Research

1 reference

1 December 2016

44

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issue

9

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page(s)

4304-16

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cites work

1 reference

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Diverse diseases from a ubiquitous process: the ribosomopathy paradox

20 March 2017

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Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae

20 March 2017

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Human diseases of the SSU processome

20 March 2017

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Crystal structure of tRNA m1G9 methyltransferase Trm10: insight into the catalytic mechanism and recognition of tRNA substrate

20 March 2017

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Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively

20 March 2017

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Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA

20 March 2017

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A translation-like cycle is a quality control checkpoint for maturing 40S ribosome subunits

20 March 2017

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Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits

20 March 2017

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Crystal structure of the eukaryotic ribosome

20 March 2017

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The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

20 March 2017

1 reference

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The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase

20 March 2017

1 reference

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Rational extension of the ribosome biogenesis pathway using network-guided genetics

20 March 2017

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Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2

20 March 2017

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Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits

20 March 2017

1 reference

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The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site

20 March 2017

1 reference

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X-ray structure of the complete ABC enzyme ABCE1 from Pyrococcus abyssi

20 March 2017

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The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases

20 March 2017

1 reference

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Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein

20 March 2017

1 reference

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Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA

20 March 2017

1 reference

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Post-transcriptional nucleotide modification and alternative folding of RNA

20 March 2017

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Deciphering structure and topology of conserved COG2042 orphan proteins

20 March 2017

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Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2

20 March 2017

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Global analysis of protein localization in budding yeast

20 March 2017

1 reference

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Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9.

20 March 2017

1 reference

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Nep1p (Emg1p), a novel protein conserved in eukaryotes and archaea, is involved in ribosome biogenesis

20 March 2017

1 reference

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Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs

20 March 2017

1 reference

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Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene.

20 March 2017

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The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3'-terminal loop of 18 S rRNA is essential in yeast

20 March 2017

1 reference

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Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1

20 March 2017

1 reference

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The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

20 March 2017

1 reference

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Optimization of ribosome structure and function by rRNA base modification

20 March 2017

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Site-specific pseudouridine formation in preribosomal RNA is guided by small nucleolar RNAs

20 March 2017

1 reference

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rRNA modifications and ribosome function

20 March 2017

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'View From A Bridge': A New Perspective on Eukaryotic rRNA Base Modification.

20 March 2017

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Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

29 September 2017

1 reference

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Analysis of two domains with novel RNA-processing activities throws light on the complex evolution of ribosomal RNA biogenesis

29 September 2017

1 reference

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Noncoding RNAs in eukaryotic ribosome biogenesis and function

29 September 2017

1 reference

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Ribosome biogenesis in the yeast Saccharomyces cerevisiae

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872110

Essential ribosome assembly factor Fap7 regulates a hierarchy of RNA-protein interactions during small ribosomal subunit biogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872110

Genetics. Mysterious ribosomopathies

29 September 2017

1 reference

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S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used?

29 September 2017

1 reference

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Ribosomopathies: human disorders of ribosome dysfunction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872110

Structure, dynamics, and function of RNA modification enzymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872110

Expanding the nucleotide repertoire of the ribosome with post-transcriptional modifications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872110

Ribosome structure and activity are altered in cells lacking snoRNPs that form pseudouridines in the peptidyl transferase center

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4872110

The phylogenetic relationships of three sulfur dependent archaebacteria

29 September 2017

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29 September 2017

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Characterization of three new snRNAs from Saccharomyces cerevisiae: snR34, snR35 and snR36

21 January 2018

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Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution

29 September 2017

1 reference

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Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates

2 June 2018

1 reference

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Cracking pre-40S ribosomal subunit structure by systematic analyses of RNA-protein cross-linking

2 June 2018

1 reference

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Loss of rRNA modifications in the decoding center of the ribosome impairs translation and strongly delays pre-rRNA processing

2 June 2018

1 reference

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Biosynthesis of a hypermodified nucleotide in Saccharomyces carlsbergensis 17S and HeLa-cell 18S ribosomal ribonucleic acid

2 June 2018

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Identities and phylogenetic comparisons of posttranscriptional modifications in 16 S ribosomal RNA from Haloferax volcanii.

2 June 2018

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Methanococcus jannaschii sp. nov., an extremely thermophilic methanogen from a submarine hydrothermal vent

21 January 2018

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Prognostic value of nucleolar protein p120 in patients with resected lung adenocarcinoma

21 January 2018

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12 December 2020

Presence of a hypermodified nucleotide in hela cell 18 S and Saccharomyces carlsbergensis 17 S ribosomal RNAs

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12 December 2020

Incorporation of 14C from [2-14C]methionine into 18 s but not 28 s RNA of Chinese hamster cells

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12 December 2020

Ribonucleoside analysis by reversed-phase high-performance liquid chromatography

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKW244

1 reference

2283651

2283651

1 reference

1 reference

1 reference