Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21 days or q28 days) for patients with advanced solid tumors. (Q27853128)

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English	Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21 days or q28 days) for patients with advanced solid tumors.	scientific article

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scholarly article

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13 November 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25672916%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21 days or q28 days) for patients with advanced solid tumors (English)

1 reference

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29 February 2020

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based on heuristic

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7

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29 February 2020

Jennifer L Winkelmann

8

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29 February 2020

Mario E Lacouture

14

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29 February 2020

11

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Alexia Iasonos

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29 February 2020

1

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David M Hyman

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29 February 2020

author name string

Alexandra E Snyder

2

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29 February 2020

Richard D Carvajal

3

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29 February 2020

John F Gerecitano

4

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29 February 2020

Martin H Voss

5

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29 February 2020

Alan L Ho

6

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29 February 2020

Megan A Stasi

9

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29 February 2020

Kelsey R Monson

10

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29 February 2020

David R Spriggs

12

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29 February 2020

Philip Bialer

13

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29 February 2020

Jerrold B Teitcher

15

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29 February 2020

Nora Katabi

16

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29 February 2020

Matthew G Fury

17

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29 February 2020

publication date

12 February 2015

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29 February 2020

Cancer Chemotherapy and Pharmacology

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29 February 2020

75

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29 February 2020

747-755

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29 February 2020

4

1 reference

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29 February 2020

https://scigraph.springernature.com/pub.10.1007/s00280-015-2693-z

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The PI3K pathway as drug target in human cancer

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21 January 2018

PIK3CA mutation H1047R is associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trials

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21 January 2018

Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor

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21 January 2018

Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors

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https://api.crossref.org/works/10.1007%2FS00280-015-2693-Z

21 January 2018

Phase I dose-escalation and -expansion study of buparlisib (BKM120), an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1007%2FS00280-015-2693-Z

21 January 2018

The PHQ-9: validity of a brief depression severity measure

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21 January 2018

A brief measure for assessing generalized anxiety disorder: the GAD-7.

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Comparative genomic analysis of primary versus metastatic colorectal carcinomas.

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Genomic and biological characterization of exon 4 KRAS mutations in human cancer

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21 January 2018

Randomized, phase II study of the insulin-like growth factor-1 receptor inhibitor IMC-A12, with or without cetuximab, in patients with cetuximab- or panitumumab-refractory metastatic colorectal cancer

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21 January 2018

Protocol for PTEN expression by immunohistochemistry in formalin-fixed paraffin-embedded human breast carcinoma

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21 January 2018

Re: New guidelines to evaluate the response to treatment in solid tumors (ovarian cancer).

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21 January 2018

Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab

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21 January 2018

Safety and pharmacokinetics of paclitaxel and the oral mTOR inhibitor everolimus in advanced solid tumours.

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21 January 2018

Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: a NCIC-CTG, phase I, open-label dose-escalation study (IND 179).

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21 January 2018

A phase 1 study of weekly everolimus (RAD001) in combination with docetaxel in patients with metastatic breast cancer

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21 January 2018

Phase 1 and pharmacokinetic study of everolimus, a mammalian target of rapamycin inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung cancer.

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21 January 2018

A phase I study of temsirolimus plus carboplatin plus paclitaxel for patients with recurrent or metastatic (R/M) head and neck squamous cell cancer (HNSCC).

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21 January 2018

A phase 1 study of everolimus plus docetaxel plus cisplatin as induction chemotherapy for patients with locally and/or regionally advanced head and neck cancer

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21 January 2018

Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials

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21 January 2018

Discovery of 2-{3-[2-(1-isopropyl-3-methyl-1H-1,2-4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide (GDC-0032): a β-sparing phosphoinositide 3-kinase inhibitor with high unbound exposure and ro

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21 January 2018

PTEN-deficient cancers depend on PIK3CB.

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21 January 2018

Nuclear PTEN controls DNA repair and sensitivity to genotoxic stress

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21 January 2018

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation

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https://pubmed.ncbi.nlm.nih.gov/25672916

12 December 2020

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Inhibition of phosphatidylinositol 3'-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models.

1 reference

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12 December 2020

based on heuristic

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Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling

1 reference

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12 December 2020

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Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis

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12 December 2020

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Identifiers

10.1007/S00280-015-2693-Z

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29 February 2020

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1 reference

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29 February 2020

2 references

13 November 2016

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25672916%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

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