Selective inhibitors of the FK506-binding protein 51 by induced fit (Q27696235)

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23 February 2020

title

Selective inhibitors of the FK506-binding protein 51 by induced fit (English)

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23 February 2020

4

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23 February 2020

Georgia Balsevich

6

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23 February 2020

Paula Fernandez-Vizarra

8

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23 February 2020

Osborne F.X. Almeida

13

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23 February 2020

Mathias V Schmidt

16

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23 February 2020

Andreas Bracher

18

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23 February 2020

12

Elisabeth B Binder

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23 February 2020

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Manfred Uhr

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23 February 2020

author name string

Steffen Gaali

1

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23 February 2020

Alexander Kirschner

2

1 reference

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23 February 2020

Serena Cuboni

3

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23 February 2020

Christian Kozany

5

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23 February 2020

Christian Namendorf

7

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23 February 2020

Claudia Sippel

9

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23 February 2020

Anthony S Zannas

10

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23 February 2020

Rika Draenert

11

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23 February 2020

Gerd Rühter

14

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23 February 2020

Chadi Touma

17

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23 February 2020

Felix Hausch

19

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23 February 2020

publication date

1 December 2014

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23 February 2020

published in

Nature Chemical Biology

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23 February 2020

volume

11

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23 February 2020

issue

1

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23 February 2020

page(s)

33-37

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Chaperoning steroidal physiology: lessons from mouse genetic models of Hsp90 and its cochaperones

23 February 2020

cites work

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FKBP51 and FKBP52 in signaling and disease

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Physiological role for the cochaperone FKBP52 in androgen receptor signaling

21 April 2017

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Cochaperone immunophilin FKBP52 is critical to uterine receptivity for embryo implantation

21 April 2017

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Essential role for Co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiology

21 April 2017

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A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51.

21 April 2017

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Crystal structures of the free and ligand-bound FK1-FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge

21 April 2017

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Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90

21 April 2017

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Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin

21 April 2017

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Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity

21 April 2017

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Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowth

21 April 2017

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Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52

21 April 2017

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Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52

21 April 2017

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Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control

21 April 2017

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21 April 2017

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21 April 2017

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21 April 2017

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Refinement of macromolecular structures by the maximum-likelihood method

21 April 2017

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

21 April 2017

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Organization and function of the FKBP52 and FKBP51 genes

21 April 2017

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The prospect of FKBP51 as a drug target.

21 January 2018

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The chemical biology of immunophilin ligands

21 January 2018

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FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform

21 January 2018

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Neuropsin cleaves EphB2 in the amygdala to control anxiety

21 January 2018

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The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress.

21 January 2018

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FK506 binding protein 5 shapes stress responsiveness: modulation of neuroendocrine reactivity and coping behavior.

21 January 2018

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Deficiency of FK506-binding protein (FKBP) 51 alters sleep architecture and recovery sleep responses to stress in mice

21 January 2018

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Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism

21 January 2018

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Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders

21 January 2018

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Targeting FKBP isoforms with small-molecule ligands

21 January 2018

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InterAKTions with FKBPs--mutational and pharmacological exploration

21 January 2018

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FKBPs and the Akt/mTOR pathway

21 January 2018

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A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules

21 January 2018

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Pseudoephedrine as a Practical Chiral Auxiliary for the Synthesis of Highly Enantiomerically Enriched Carboxylic Acids, Alcohols, Aldehydes, and Ketones

21 January 2018

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Comparative analysis of calcineurin inhibition by complexes of immunosuppressive drugs with human FK506 binding proteins

21 January 2018

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FK1706, a novel non-immunosuppressive immunophilin: neurotrophic activity and mechanism of action.

21 January 2018

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Genetically engineered analogs of ascomycin for nerve regeneration

21 January 2018

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Unraveling the role of peptidyl-prolyl isomerases in neurodegeneration

21 January 2018

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Stress and affective disorders: animal models elucidating the molecular basis of neuroendocrine-behavior interactions

21 January 2018

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Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice.

21 January 2018

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When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders

21 January 2018

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Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions

21 January 2018

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Fluorescent probes to characterise FK506-binding proteins

21 January 2018

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Total synthesis of antascomicin B.

21 January 2018

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Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses.

21 January 2018

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Inflammatory T helper 17 cells promote depression-like behavior in mice

21 January 2018

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21 January 2018

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Mice selected for high versus low stress reactivity: a new animal model for affective disorders

21 January 2018

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Spherically averaged phased translation function and its application to the search for molecules and fragments in electron-density maps

21 January 2018

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Differences between mice strains in response to paroxetine in the forced swimming test: involvement of serotonergic or noradrenergic systems

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25436518

12 December 2020

inferred from PubMed ID database lookup

Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25436518

12 December 2020

inferred from PubMed ID database lookup

Combined Dexamethasone/Corticotropin Releasing Hormone Test Predicts Treatment Response in Major Depression–A Potential Biomarker?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25436518

12 December 2020

inferred from PubMed ID database lookup

On the treatment of negative intensity observations

1 reference

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEMBIO.1699

2 references

Consolidated OpenCitations Corpus – April 2017

4093552

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25436518%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

23 February 2020

1050496229

0 references

4093552

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4093552

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25436518%20AND%20SRC:MED&resulttype=core&format=json