HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders (Q27691344)

Wool GD

series ordinal

2

1 reference

Reardon CA

series ordinal

3

1 reference

publication date

2010

1 reference

Current Pharmaceutical Design

published in

1 reference

volume

16

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issue

28

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page(s)

3173-84

1 reference

The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins

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An apoA-I mimetic peptide containing a proline residue has greater in vivo HDL binding and anti-inflammatory ability than the 4F peptide

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Apolipoprotein A-I mimetic peptide helix number and helix linker influence potentially anti-atherogenic properties

29 September 2017

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Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients

29 September 2017

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The effect of apolipoprotein mimetic peptides in inflammatory disorders other than atherosclerosis

29 September 2017

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Structural requirements for antioxidative and anti-inflammatory properties of apolipoprotein A-I mimetic peptides

29 September 2017

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29 September 2017

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Atherosclerosis and vascular disease: effects of peptide mimetics of apolipoproteins.

29 September 2017

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Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes

29 September 2017

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Janus kinase 2 modulates the lipid-removing but not protein-stabilizing interactions of amphipathic helices with ABCA1.

29 September 2017

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Apolipoprotein A-I mimetic peptides

29 September 2017

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D-4F, an apolipoprotein A-I mimetic peptide, inhibits the inflammatory response induced by influenza A infection of human type II pneumocytes

29 September 2017

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Serum amyloid A promotes ABCA1-dependent and ABCA1-independent lipid efflux from cells

29 September 2017

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Model class A and class L peptides increase the production of apoA-I-containing lipoproteins in HepG2 cells

29 September 2017

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29 September 2017

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HDL and the inflammatory response induced by LDL-derived oxidized phospholipids

29 September 2017

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An apolipoprotein E synthetic peptide targets to lipoproteins in plasma and mediates both cellular lipoprotein interactions in vitro and acute clearance of cholesterol-rich lipoproteins in vivo

29 September 2017

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Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio

29 September 2017

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Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse

29 September 2017

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29 September 2017

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29 September 2017

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High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies

29 September 2017

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Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein

29 September 2017

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Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall

29 September 2017

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Anti-inflammatory apoA-I-mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I.

2 June 2018

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Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet

2 June 2018

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Oral small peptides render HDL antiinflammatory in mice and monkeys and reduce atherosclerosis in ApoE null mice.

2 June 2018

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2 June 2018

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Effect of an arginine-rich amphipathic helical peptide on plasma cholesterol in dyslipidemic mice

2 June 2018

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Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3.

2 June 2018

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Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides

2 June 2018

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Studies of synthetic peptide analogs of the amphipathic helix. Structure of complexes with dimyristoyl phosphatidylcholine

2 June 2018

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Turnover of synthetic class A amphipathic peptide analogues of exchangeable apolipoproteins in rats. Correlation with physical properties

2 June 2018

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2 June 2018

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An apolipoprotein A-I mimetic dose-dependently increases the formation of prebeta1 HDL in human plasma

27 November 2018

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Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits

27 November 2018

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ApoA-I mimetic peptides with differing ability to inhibit atherosclerosis also exhibit differences in their interactions with membrane bilayers.

27 November 2018

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Peptides derived from serum amyloid A prevent, and reverse, aortic lipid lesions in apoE-/- mice

27 November 2018

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An oral apoJ peptide renders HDL antiinflammatory in mice and monkeys and dramatically reduces atherosclerosis in apolipoprotein E-null mice.

27 November 2018

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Apolipoprotein E mimetic Peptide dramatically lowers plasma cholesterol and restores endothelial function in watanabe heritable hyperlipidemic rabbits

27 November 2018

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D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice

27 November 2018

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Differential effects of apolipoprotein A-I-mimetic peptide on evolving and established atherosclerosis in apolipoprotein E-null mice.

27 November 2018

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Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice

27 November 2018

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Aromatic residue position on the nonpolar face of class a amphipathic helical peptides determines biological activity

27 November 2018

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Identification of an apolipoprotein A-I structural element that mediates cellular cholesterol efflux and stabilizes ATP binding cassette transporter A1.

27 November 2018

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Inflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment

27 November 2018

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L-4F, an Apolipoprotein A-1 Mimetic, Dramatically Improves Vasodilation in Hypercholesterolemia and Sickle Cell Disease

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087816

Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway

27 November 2018

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Serum paraoxonase: effect of the apolipoprotein composition of HDL and the acute phase response

27 November 2018

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Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087816

Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide

27 November 2018

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Cationic domain 141-150 of apoE covalently linked to a class A amphipathic helix enhances atherogenic lipoprotein metabolism in vitro and in vivo.

27 November 2018

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A new synthetic class A amphipathic peptide analogue protects mice from diet-induced atherosclerosis.

27 November 2018

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Studies of synthetic peptide analogs of the amphipathic helix. Effect of charge distribution, hydrophobicity, and secondary structure on lipid association and lecithin:cholesterol acyltransferase activation

27 November 2018

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12 December 2020

A 70-kDa apolipoprotein designated ApoJ is a marker for subclasses of human plasma high density lipoproteins

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12 December 2020

Effect of end group blockage on the properties of a class A amphipathic helical peptide

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12 December 2020

Interactions of synthetic peptide analogs of the class A amphipathic helix with lipids. Evidence for the snorkel hypothesis

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12 December 2020

HDL content and composition in acute phase response in three species: triglyceride enrichment of HDL a factor in its decrease

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12 December 2020

Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants

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12 December 2020

The receptor binding domain of apolipoprotein E, linked to a model class A amphipathic helix, enhances internalization and degradation of LDL by fibroblasts

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12 December 2020