Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches (Q35860029)

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scientific article published in June 2008

Language	Label	Description	Also known as
English	Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches	scientific article published in June 2008

Statements

scholarly article

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches (English)

1 reference

Europe PubMed Central

10 August 2017

HDL cholesterol

0 references

1 reference

based on heuristic

inferred from title

author name string

Emil M deGoma

1

1 reference

Europe PubMed Central

10 August 2017

Rolando L deGoma

2

1 reference

Europe PubMed Central

10 August 2017

Daniel J Rader

3

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

1 June 2008

1 reference

Europe PubMed Central

10 August 2017

Journal of the American College of Cardiology

1 reference

Europe PubMed Central

10 August 2017

51

1 reference

Europe PubMed Central

10 August 2017

2199-2211

1 reference

Europe PubMed Central

10 August 2017

23

1 reference

Europe PubMed Central

10 August 2017

Platelet activation and atherothrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

11 July 2018

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

11 July 2018

Effects of torcetrapib in patients at high risk for coronary events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

11 July 2018

Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

11 July 2018

Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia

1 reference

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11 July 2018

Effect of torcetrapib on the progression of coronary atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

11 July 2018

Endothelial function and dysfunction: testing and clinical relevance

1 reference

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11 July 2018

Molecular regulation of HDL metabolism and function: implications for novel therapies

1 reference

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11 July 2018

Endothelial and antithrombotic actions of HDL.

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11 July 2018

Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport

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11 July 2018

Accumulation of chylomicron remnants and impaired vascular reactivity occur in subjects with isolated low HDL cholesterol: effects of niacin treatment.

1 reference

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11 July 2018

Direct evidence in vivo of impaired macrophage-specific reverse cholesterol transport in ATP-binding cassette transporter A1-deficient mice

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11 July 2018

Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet

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11 July 2018

Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo

1 reference

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11 July 2018

Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation

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11 July 2018

Low-density lipoprotein subfractions and the long-term risk of ischemic heart disease in men: 13-year follow-up data from the Québec Cardiovascular Study

1 reference

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11 July 2018

Antiinflammatory properties of HDL.

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11 July 2018

Efficacy of fenofibrate and simvastatin on endothelial function and inflammatory markers in patients with combined hyperlipidemia: relations with baseline lipid profiles

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11 July 2018

Endothelial nitric oxide synthase, caveolae and the development of atherosclerosis

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11 July 2018

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

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11 July 2018

A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation

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11 July 2018

Increased ABCA1 activity protects against atherosclerosis.

1 reference

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11 July 2018

Effect of high-density lipoproteins on the expression of adhesion molecules in endothelial cells

1 reference

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11 July 2018

Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins: an idea whose time for testing is coming, part II.

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11 July 2018

Intravenous apoA-I/lecithin discs increase pre-beta-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans

1 reference

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11 July 2018

Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL

1 reference

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11 July 2018

High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase

1 reference

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11 July 2018

Effect of up-regulating individual steps in the reverse cholesterol transport pathway on reverse cholesterol transport in normolipidemic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

11 July 2018

Elevation of plasma high-density lipoprotein concentration reduces interleukin-1-induced expression of E-selectin in an in vivo model of acute inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

11 July 2018

Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

11 July 2018

Evidence that high-density lipoprotein cholesterol is an independent predictor of acute platelet-dependent thrombus formation.

1 reference

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11 July 2018

Reconstituted HDL containing human apolipoprotein A-1 reduces VCAM-1 expression and neointima formation following periadventitial cuff-induced carotid injury in apoE null mice

1 reference

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11 July 2018

Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans

1 reference

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11 July 2018

High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C.

1 reference

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Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men.

1 reference

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11 July 2018

Differential effects of reconstituted high-density lipoprotein on coagulation, fibrinolysis and platelet activation during human endotoxemia

1 reference

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11 July 2018

Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels

1 reference

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11 July 2018

Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma

1 reference

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11 July 2018

Cholesterol net transport, esterification, and transfer in human hyperlipidemic plasma

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11 July 2018

Relationship of the parameters of body cholesterol metabolism with plasma levels of HDL cholesterol and the major HDL apoproteins

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11 July 2018

Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study.

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11 July 2018

Monocyte migration into the subendothelial space of a coculture of adult human aortic endothelial and smooth muscle cells

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11 July 2018

Diet and 20-year mortality from coronary heart disease. The Ireland-Boston Diet-Heart Study

1 reference

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11 July 2018

Platelet and vessel wall interaction and the genesis of atherosclerosis

1 reference

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11 July 2018

High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein

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A simplified micro-method for quantification of fecal excretion of neutral and acidic sterols for outpatient studies in humans

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11 July 2018

Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein

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Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins.

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Binding of transition metals by apolipoprotein A-I-containing plasma lipoproteins: inhibition of oxidation of low density lipoproteins

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Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells

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11 July 2018

Clinical significance of high-density lipoprotein cholesterol in patients with low low-density lipoprotein cholesterol

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24 September 2018

Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies.

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24 September 2018

Illuminating HDL--is it still a viable therapeutic target?

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24 September 2018

Beyond low-density lipoprotein cholesterol: defining the role of low-density lipoprotein heterogeneity in coronary artery disease.

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Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL.

1 reference

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Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function.

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The effect of high-density-lipoprotein on thrombus formation on and endothelial cell attachement to biomaterial surfaces.

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Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo.

1 reference

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Ability of serum to decrease cellular acylCoA:cholesterol acyl transferase activity predicts cardiovascular outcomes.

1 reference

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24 September 2018

Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits

1 reference

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Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide.

1 reference

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24 September 2018

An oral apoJ peptide renders HDL antiinflammatory in mice and monkeys and dramatically reduces atherosclerosis in apolipoprotein E-null mice.

1 reference

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D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice

1 reference

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Homozygosity for factor V Leiden leads to enhanced thrombosis and atherosclerosis in mice.

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24 September 2018

Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice

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Reconstituted high-density lipoprotein inhibits thrombin-induced endothelial tissue factor expression through inhibition of RhoA and stimulation of phosphatidylinositol 3-kinase but not Akt/endothelial nitric oxide synthase

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24 September 2018

Inflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment

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24 September 2018

Genetics of increased HDL cholesterol levels: insights into the relationship between HDL metabolism and atherosclerosis

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24 September 2018

Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo

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24 September 2018

Relation between high-density lipoprotein cholesterol and peripheral vasomotor function.

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24 September 2018

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24 September 2018

High-density lipoprotein stimulates endothelial cell migration and survival through sphingosine 1-phosphate and its receptors

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24 September 2018

L-4F, an apolipoprotein A-1 mimetic, restores nitric oxide and superoxide anion balance in low-density lipoprotein-treated endothelial cells.

1 reference

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24 September 2018

Direct association between high-density lipoprotein cholesterol and endothelial function in hyperlipemia

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Influenza infection promotes macrophage traffic into arteries of mice that is prevented by D-4F, an apolipoprotein A-I mimetic peptide

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24 September 2018

A novel mechanism for the beneficial vascular effects of high-density lipoprotein cholesterol: enhanced vasorelaxation and increased endothelial nitric oxide synthase expression

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24 September 2018

High-density lipoprotein restores endothelial function in hypercholesterolemic men.

1 reference

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24 September 2018

Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study

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24 September 2018

Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol

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24 September 2018

Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease

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24 September 2018

A cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipids

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24 September 2018

Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids

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24 September 2018

High-dose recombinant apolipoprotein A-I(milano) mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein e-deficient mice. Potential implications for acute plaque stabilization

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24 September 2018

A new synthetic class A amphipathic peptide analogue protects mice from diet-induced atherosclerosis.

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24 September 2018

Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial

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24 September 2018

Inability of plasma high-density lipoproteins to inhibit cell adhesion molecule expression in human coronary artery endothelial cells

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24 September 2018

High density lipoprotein prevents oxidized low density lipoprotein-induced inhibition of endothelial nitric-oxide synthase localization and activation in caveolae.

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24 September 2018

Effects of lipids and lipoproteins on thrombosis and rheology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

24 September 2018

Compared with dietary monounsaturated and saturated fat, polyunsaturated fat protects African green monkeys from coronary artery atherosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315104

24 September 2018

Binding of apoE-rich high density lipoprotein particles by saturable sites on human blood platelets inhibits agonist-induced platelet aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanogram nitrite and nitrate determination in environmental and biological materials by vanadium (III) reduction with chemiluminescence detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoprotein or apolipoprotein A-I concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating cell adhesion molecules are correlated with ultrasound-based assessment of carotid atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of arterial thrombus formation by ApoA1 Milano

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reverse cholesterol transport and atherosclerosis regression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constantly low HDL-cholesterol concentration relates to endothelial dysfunction and increased in vivo LDL-oxidation in healthy young men

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An increased coronary risk is paradoxically associated with common cholesteryl ester transfer protein gene variations that relate to higher high-density lipoprotein cholesterol: a population-based study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-density lipoprotein and the risk of recurrent venous thromboembolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo reverse cholesterol transport from macrophages lacking ABCA1 expression is impaired

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelium-dependent and -independent functions are impaired in patients with coronary heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoproteins inhibit the secretion of tissue plasminogen activator from human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cell culture system for screening human serum for ability to promote cellular cholesterol efflux. Relations between serum components and efflux, esterification, and transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of VCAM-1 in rabbit iliac arteries is associated with vasodilator dysfunction of regenerated endothelium following balloon injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic cholesteryl ester transfer protein deficiency is extremely frequent in the Omagari area of Japan. Marked hyperalphalipoproteinemia caused by CETP gene mutation is not associated with longevity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstituted high density lipoprotein (rHDL) modulates platelet activity in vitro and ex vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors influencing the ability of HDL to inhibit expression of vascular cell adhesion molecule-1 in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of high density lipoprotein on endothelium-dependent vasodilatation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibody against vascular cell adhesion molecule-1 inhibits neointimal formation after periadventitial carotid artery injury in genetically hypercholesterolemic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ability of reconstituted high density lipoproteins to inhibit cytokine-induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma lipoproteins, hemostasis and thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion of monocytes to arterial endothelium and initiation of atherosclerosis are critically dependent on vascular cell adhesion molecule-1 gene dosage

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PLTP deficiency improves the anti-inflammatory properties of HDL and reduces the ability of LDL to induce monocyte chemotactic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma high density lipoproteins inhibit the activation of coagulation factor X by factor VIIa and tissue factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18534265

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JACC.2008.03.016

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

ResearchGate publication ID

0 references

Sitelinks

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