RRP6 from Trypanosoma brucei: crystal structure of the catalytic domain, association with EAP3 and activity towards structured and non-structured RNA substrates (Q27681857)

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English	RRP6 from Trypanosoma brucei: crystal structure of the catalytic domain, association with EAP3 and activity towards structured and non-structured RNA substrates	scientific article

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8 March 2020

RRP6 from Trypanosoma brucei: crystal structure of the catalytic domain, association with EAP3 and activity towards structured and non-structured RNA substrates (English)

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8 March 2020

crystal structure

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Trypanosoma brucei

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3

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8 March 2020

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Rosicler L Barbosa

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8 March 2020

Pierre Legrand

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Blandine Pineau

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8 March 2020

Andrew Thompson

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8 March 2020

Beatriz G Guimarães

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18 February 2014

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8 March 2020

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8 March 2020

e89138

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Creative Commons Attribution 4.0 International

18 February 2014

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Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex

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20 March 2017

Activities of human RRP6 and structure of the human RRP6 catalytic domain

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20 March 2017

The C-terminal region of the exosome-associated protein Rrp47 is specifically required for box C/D small nucleolar RNA 3'-maturation

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20 March 2017

The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation

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20 March 2017

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

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20 March 2017

Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family

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20 March 2017

Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways

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20 March 2017

C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing

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The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

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20 March 2017

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20 March 2017

Assembly of the yeast exoribonuclease Rrp6 with its associated cofactor Rrp47 occurs in the nucleus and is critical for the controlled expression of Rrp47

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20 March 2017

Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p

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20 March 2017

The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3928423

20 March 2017

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

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20 March 2017

Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs.

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20 March 2017

Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formation

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The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases

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29 September 2017

The subcellular localisation of trypanosome RRP6 and its association with the exosome

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29 September 2017

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Identifiers

10.1371/JOURNAL.PONE.0089138

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2014PLoSO...989138B

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