Complete integrin headpiece opening in eight steps (Q27678790)

24 June 2017

Complete integrin headpiece opening in eight steps (English)

1 reference

24 June 2017

0 references

Jieqing Zhu

1

1 reference

24 June 2017

Jianghai Zhu

series ordinal

2

1 reference

24 June 2017

Timothy A Springer

series ordinal

3

1 reference

24 June 2017

language of work or name

English

0 references

publication date

1 June 2013

1 reference

24 June 2017

Journal of Cell Biology

1 reference

24 June 2017

201

1 reference

24 June 2017

7

1 reference

24 June 2017

1053-1068

1 reference

α(V)β(3) integrin crystal structures and their functional implications

24 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structure-Guided Design of a High-Affinity Platelet Integrin IIb 3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Latent TGF-β structure and activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Closed headpiece of integrin IIb 3 and its complex with an IIb 3-specific antagonist that does not induce opening

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structure of an integrin with an αI domain, complement receptor type 4

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin α IIb β 3

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

A specific interface between integrin transmembrane helices and affinity for ligand

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Crystal structure of the extracellular segment of integrin alpha Vbeta3

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Phasercrystallographic software

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Scaling and assessment of data quality

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Dynamic personalities of proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structural basis of integrin regulation and signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

GARP regulates the bioavailability and activation of TGFβ.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Integrin inside-out signaling and the immunological synapse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Regulation of integrin affinity on cell surfaces

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Intact alphaIIbbeta3 integrin is extended after activation as measured by solution X-ray scattering and electron microscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Modulation of integrin activation by an entropic spring in the {beta}-knee

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Integrin activation dynamics between the RGD-binding site and the headpiece hinge

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Tests of the extension and deadbolt models of integrin activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

How the headpiece hinge angle is opened: New insights into the dynamics of integrin activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Electron tomography reveals diverse conformations of integrin alphaIIbbeta3 in the active state

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

UR-3216: a new generation oral platelet GPIIb/IIIa antagonist

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Novel activating and inactivating mutations in the integrin beta1 subunit A domain.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structure of integrin alpha5beta1 in complex with fibronectin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structural requirements for activation in alphaIIb beta3 integrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Structural insights into how the MIDAS ion stabilizes integrin binding to an RGD peptide under force

2 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201212037

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201212037

Allosteric beta1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201212037

Rationally designed integrin beta3 mutants stabilized in the high affinity conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201212037

Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201212037

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201212037

Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201212037

Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691460

Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23798730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201212037

1 reference

OpenCitations bibliographic resource ID

24 June 2017

2778225

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference