Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α (Q27674529)

7

object named as

William L Jorgensen

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Peter C Gareiss

6

object named as

Peter C Gareiss

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Hyun Seop Tae

5

object named as

Hyun Seop Tae

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author name string

Dennis L Buckley

1

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Jeffrey L Gustafson

2

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Anke G Roth

4

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Craig M Crews

Angewandte Chemie International Edition

9

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language of work or name

English

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publication date

12 November 2012

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published in

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volume

51

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issue

46

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page(s)

11463-7

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cites work

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Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

20 March 2017

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Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain

20 March 2017

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Structural conservation of druggable hot spots in protein-protein interfaces

20 March 2017

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An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase

20 March 2017

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

20 March 2017

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20 March 2017

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Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors

29 September 2017

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Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets

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29 September 2017

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29 September 2017

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29 September 2017

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Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer

29 September 2017

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Fluorescence polarization competition assay: the range of resolvable inhibitor potency is limited by the affinity of the fluorescent ligand

29 September 2017

1 reference

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Peptide blockade of HIFalpha degradation modulates cellular metabolism and angiogenesis

29 September 2017

1 reference

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Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

29 September 2017

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Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase

29 September 2017

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Donor-acceptor (electronic) coupling in the precursor complex to organic electron transfer: intermolecular and intramolecular self-exchange between phenothiazine redox centers

2 June 2018

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Crossref

https://api.crossref.org/works/10.1002%2FANIE.201206231

Structure-based design of potent, conformationally constrained Smac mimetics

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23065727

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23065727

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/ANIE.201206231

1 reference

2676699

2676699

1 reference

1 reference

1 reference