Trapping of palindromic ligands within native transthyretin prevents amyloid formation (Q27665687)

22 June 2017

Trapping of palindromic ligands within native transthyretin prevents amyloid formation (English)

1 reference

22 June 2017

18

1 reference

22 June 2017

Simon E Kolstoe

1

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Anthony G Coyne

Anthony Coyne

9

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Timothy D Warner

Timothy D Warner

11

0 references

Steven V. Ley

Steven V Ley

15

0 references

Carol V. Robinson

Carol V Robinson

16

0 references

Stephen P. Wood

17

Stephen P Wood

1 reference

22 June 2017

Palma P Mangione

2

1 reference

22 June 2017

Vittorio Bellotti

3

1 reference

22 June 2017

Graham W Taylor

4

1 reference

22 June 2017

Glenys A Tennent

5

1 reference

22 June 2017

Stéphanie Deroo

6

1 reference

22 June 2017

Angus J Morrison

7

1 reference

22 June 2017

Alexander J A Cobb

8

1 reference

22 June 2017

Margaret G McCammon

10

1 reference

22 June 2017

Jane Mitchell

12

1 reference

22 June 2017

Raj Gill

13

1 reference

22 June 2017

Martin D Smith

14

1 reference

22 June 2017

language of work or name

English

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publication date

8 November 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

22 June 2017

1 reference

22 June 2017

107

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22 June 2017

47

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22 June 2017

20483-20488

1 reference

Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors

22 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

The integration of macromolecular diffraction data

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Natural history and outcome in systemic AA amyloidosis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Targeting C-reactive protein for the treatment of cardiovascular disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Native state kinetic stabilization as a strategy to ameliorate protein misfolding diseases: a focus on the transthyretin amyloidoses.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Hereditary transthyretin amyloidosis: molecular basis and therapeutical strategies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Outcome in systemic AL amyloidosis in relation to changes in concentration of circulating free immunoglobulin light chains following chemotherapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Evaluating the binding selectivity of transthyretin amyloid fibril inhibitors in blood plasma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Deuterium-proton exchange on the native wild-type transthyretin tetramer identifies the stable core of the individual subunits and indicates mobility at the subunit interface

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Thyroxine binding to transthyretin (TTR) variants--two variants (TTR Pro 55 and TTR Met 111) with a particularly low binding affinity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Clinical improvement and amyloid regression after liver transplantation in hereditary transthyretin amyloidosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Senile amyloidosis: a protean manifestation of the aging process

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

L55P transthyretin accelerates subunit exchange and leads to rapid formation of hybrid tetramers.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280-nm absorption coefficients for proteins and glycoproteins from amino acid sequences.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996680

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

Synthesis, structure, and activity of diclofenac analogues as transthyretin amyloid fibril formation inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

Structures of human transthyretin complexed with thyroxine at 2.0 A resolution and 3',5'-dinitro-N-acetyl-L-thyronine at 2.2 A resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

Destabilization of transthyretin by pathogenic mutations in the DE loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

Biophysical analysis of normal transthyretin: implications for fibril formation in senile systemic amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

Computer graphics in drug design: molecular modeling of thyroid hormone-prealbumin interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1008255107

Biochemical effect of liver transplantation in two Swedish patients with familial amyloidotic polyneuropathy (FAP-met30)

21 January 2018

1 reference

12 December 2020

Thyroxine binding to transthyretin Met 119. Comparative studies of different heterozygotic carriers and structural analysis

1 reference

12 December 2020

Thyroxine interactions with transthyretin: a comparison of 10 different naturally occurring human transthyretin variants

1 reference

12 December 2020

Retinoid binding to retinol-binding protein and the interference with the interaction with transthyretin

1 reference

12 December 2020

Frequency and distribution of senile cardiovascular amyloid. A clinicopathologic correlation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1008255107

1 reference

OpenCitations bibliographic resource ID

22 June 2017

0 references

2025999

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference