Antibody recognition of a unique tumor-specific glycopeptide antigen (Q27661722)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20479270%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Antibody recognition of a unique tumor-specific glycopeptide antigen (English)

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2 February 2020

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10

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2 February 2020

author name string

Cory L Brooks

1

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2 February 2020

Andrea Schietinger

2

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2 February 2020

Svetlana N Borisova

3

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2 February 2020

Peter Kufer

4

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2 February 2020

Mark Okon

5

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2 February 2020

Tomoko Hirama

6

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2 February 2020

C Roger Mackenzie

7

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2 February 2020

Lai-Xi Wang

8

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2 February 2020

Hans Schreiber

9

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2 February 2020

language of work or name

English

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publication date

17 May 2010

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Proceedings of the National Academy of Sciences of the United States of America

2 February 2020

published in

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2 February 2020

volume

107

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2 February 2020

issue

22

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2 February 2020

page(s)

10056-10061

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Affinity maturation increases the stability and plasticity of the Fv domain of anti-protein antibodies

2 February 2020

cites work

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20 March 2017

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The crystal structure of a plant lectin in complex with the Tn antigen

20 March 2017

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Crystal structure at 1.95 A resolution of the breast tumour-specific antibody SM3 complexed with its peptide epitope reveals novel hypervariable loop recognition

20 March 2017

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Structural insights into the evolution of an antibody combining site

20 March 2017

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20 March 2017

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SRCL/CL-P1 recognizes GalNAc and a carcinoma-associated antigen, Tn antigen

22 April 2017

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The role of podoplanin in tumor progression and metastasis.

20 March 2017

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Specificity in cancer immunotherapy

29 September 2017

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Human tumor antigens Tn and sialyl Tn arise from mutations in Cosmc

29 September 2017

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A mutant chaperone converts a wild-type protein into a tumor-specific antigen

29 September 2017

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Immunology of O-glycosylated proteins: approaches to the design of a MUC1 glycopeptide-based tumor vaccine

29 September 2017

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O-glycosylated versus non-glycosylated MUC1-derived peptides as potential targets for cytotoxic immunotherapy of carcinoma.

29 September 2017

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Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

29 September 2017

1 reference

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Molecular basis of incomplete O-glycan synthesis in MCF-7 breast cancer cells: putative role of MUC6 in Tn antigen expression

29 September 2017

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Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours

29 September 2017

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Carbohydrate vaccines as immunotherapy for cancer

29 September 2017

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Tumor-Associated Carbohydrate Antigens Defining Tumor Malignancy: Basis for Development of Anti-Cancer Vaccines

29 September 2017

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Mutant epidermal growth factor receptors as targets for cancer therapy

29 September 2017

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Production and functional characterization of two mouse/human chimeric antibodies with specificity for the tumor-associated Tn-antigen.

29 September 2017

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Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Differential expression of the cancer associated antigens T (Thomsen-Friedenreich) and Tn to the skin in primary and metastatic carcinomas

29 September 2017

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Augmenting the immunogenicity of carbohydrate tumor antigens

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Analysis by surface plasmon resonance of the influence of valence on the ligand binding affinity and kinetics of an anti-carbohydrate antibody

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Interactions of protein antigens with antibodies

29 September 2017

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Exploiting altered glycosylation patterns in cancer: progress and challenges in diagnosis and therapy

29 September 2017

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Epitopic structure of Tn glycophorin A for an anti-Tn antibody (MLS 128).

29 September 2017

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Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells

29 September 2017

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Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin.

29 September 2017

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Blood group A cross-reacting epitope defined by monoclonal antibodies NCC-LU-35 and -81 expressed in cancer of blood group O or B individuals: its identification as Tn antigen

29 September 2017

1 reference

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The human repertoire of antibody specificities against Thomsen-Friedenreich and Tn-carcinoma-associated antigens as defined by human monoclonal antibodies

29 September 2017

1 reference

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Structural polymorphism within the amino-terminal region of MM, NN, and MN glycoproteins (glycophorins) of the human erythrocyte membrane

29 September 2017

1 reference

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Mutational analysis of the affinity maturation of antibody 48G7.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Carbohydrates and antigen recognition by T cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Perspectives on the significance of altered glycosylation of glycoproteins in cancer

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Simple mucin-type carbohydrate antigens (T, sialosyl-T, Tn and sialosyl-Tn) in breast carcinogenesis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915176107

Molecular cloning of a monoclonal anti-tumor antibody specific for the Tn antigen and expression of an active single-chain Fv fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915176107

Idiotypes of pre-existing human anti-carcinoma anti-T and anti-Tn antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915176107

NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915176107

Protein glycosylation: chaperone mutation in Tn syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0915176107

Design, synthesis, radiolabeling and in vitro and in vivo characterization of tumor-antigen- and antibody-derived peptides for the detection of breast cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Purification of human anti-TF (Thomsen-Friedenreich) and anti-Tn antibodies by affinity chromatography on glycophorin A derivatives and characterization of the antibodies by microtiter plate ELISA.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2890472

Carbohydrate array analysis of anti-Tn antibodies and lectins reveals unexpected specificities: implications for diagnostic and vaccine development

27 November 2018

1 reference

12 December 2020

Functional characterization of the somatic hypermutation process leading to antibody D1.3, a high affinity antibody directed against lysozyme

1 reference

12 December 2020

Distribution of Tn antigen recognized by an anti-Tn monoclonal antibody (MLS128) in normal and malignant tissues of the digestive tract

1 reference

12 December 2020

Tn epitopes, immunoreactive with ordinary anti-Tn antibodies, on normal, desialylated human erythrocytes and on Thomsen-Friedenreich antigen isolated therefrom

1 reference

12 December 2020

Structure/activity studies of the anti-MUC1 monoclonal antibody C595 and synthetic MUC1 mucin-core-related peptides and glycopeptides

1 reference

12 December 2020

Simple mucins (T, sialosyl-T, Tn and sialosyl-Tn) are not diagnostic for malignant breast lesions

1 reference

12 December 2020

Blood group Tn-active macromolecules from human carcinomas and erythrocytes: characterization of and specific reactivity with mono- and poly-clonal anti-Tn antibodies induced by various immunogens

1 reference

12 December 2020

Polypeptide secondary structure determination by nuclear magnetic resonance observation of short proton-proton distances

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0915176107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20479270%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

0 references

1 reference

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2 February 2020

PubMed publication ID

20479270

1 reference