Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies (Q30841593)

3 September 2017

Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies (English)

1 reference

3 September 2017

1 reference

P S Daugherty

1

1 reference

3 September 2017

G Chen

series ordinal

2

1 reference

3 September 2017

B L Iverson

series ordinal

3

1 reference

3 September 2017

G Georgiou

series ordinal

4

1 reference

3 September 2017

language of work or name

English

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publication date

1 February 2000

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 September 2017

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3 September 2017

97

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3 September 2017

2029-2034

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3 September 2017

5

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Optimal screening of surface-displayed polypeptide libraries

3 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Development of an optimized expression system for the screening of antibody libraries displayed on the Escherichia coli surface.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Antibody affinity maturation using bacterial surface display.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Directed evolution of a thermostable esterase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Antibody phage display technology and its applications.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

When blind is better: protein design by evolution.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Engineering the steroid-specificity of an anti-17beta-estradiol Fab by random mutagenesis and competitive phage panning

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Directed evolution of an aspartate aminotransferase with new substrate specificities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Enzyme engineering reaches the boiling point

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

DNA shuffling of a family of genes from diverse species accelerates directed evolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Directed evolution of enzyme catalysts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Generation of large libraries of random mutants in Bacillus subtilis by PCR-based plasmid multimerization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Yeast surface display for screening combinatorial polypeptide libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Optimization of DNA shuffling for high fidelity recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Exploring the functional robustness of an enzyme by in vitro evolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Contribution of antibody heavy chain CDR1 to digoxin binding analyzed by random mutagenesis of phage-displayed Fab 26-10.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Randomization of genes by PCR mutagenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

Production of Microcell Hybrids

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.030527597

Directed evolution of a fungal peroxidase

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.030527597

The effect of high-frequency random mutagenesis on in vitro protein evolution: a study on TEM-1 beta-lactamase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15748

In vitro scanning saturation mutagenesis of all the specificity determining residues in an antibody binding site

25 November 2018

1 reference

12 December 2020

Direct random mutagenesis of gene-sized DNA fragments using polymerase chain reaction

1 reference

12 December 2020

Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain

1 reference

12 December 2020

Affinity maturation of phage-displayed peptide ligands

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.030527597

1 reference

release_htnax7caajbdbhqsd5o5kw3bhy

3 September 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/htnax7caajbdbhqsd5o5kw3bhy

24 November 2022

mapped directly with Wikidata item

1 reference

3 September 2017

1 reference