Crystal Structure of Thioflavin T Bound to the Peripheral Site of Torpedo californica Acetylcholinesterase Reveals How Thioflavin T Acts as a Sensitive Fluorescent Reporter of Ligand Binding to the Acylation Site (Q27650721)

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Language	Label	Description	Also known as
English	Crystal Structure of Thioflavin T Bound to the Peripheral Site of Torpedo californica Acetylcholinesterase Reveals How Thioflavin T Acts as a Sensitive Fluorescent Reporter of Ligand Binding to the Acylation Site	scientific article

Statements

scholarly article

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Crystal Structure of Thioflavin T Bound to the Peripheral Site of Torpedo californica Acetylcholinesterase Reveals How Thioflavin T Acts as a Sensitive Fluorescent Reporter of Ligand Binding to the Acylation Site (English)

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crystal structure

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1 reference

based on heuristic

inferred from title

Pacific electric ray

object named as

Torpedo californica

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based on heuristic

inferred from title

3

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Joel L. Sussman

object named as

Joel L Sussman

4

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author name string

Michal Harel

1

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Leilani K Sonoda

2

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Terrone L Rosenberry

5

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language of work or name

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publication date

25 June 2008

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Journal of the American Chemical Society

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130

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25

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7856-61

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Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3923376

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Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity

1 reference

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Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site

1 reference

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1 reference

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1 reference

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1 reference

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Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer's disease.

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1 reference

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1 reference

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1 reference

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Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites.

1 reference

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Allosteric modulation of acetylcholinesterase activity by peripheral ligands involves a conformational transition of the anionic subsite.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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The advantages of using a modified microbatch method for rapid screening of protein crystallization conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18512913

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inferred from PubMed ID database lookup

Purification and crystallization of a dimeric form of acetylcholinesterase from Torpedo californica subsequent to solubilization with phosphatidylinositol-specific phospholipase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/18512913

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18512913

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1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA7109822

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