Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2 (Q27641363)

2

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Andrew L Kung

3

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Dennis S France

4

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Gerhard Wagner

5

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Michael J Eck

Nature structural biology

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publication date

July 2003

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published in

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volume

10

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page(s)

504-12

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issue

7

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cites work

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Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803

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Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2

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Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1.

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msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation

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MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity

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The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors

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Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein

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Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

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The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation

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Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

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CREB-binding protein and p300 in transcriptional regulation

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The atomic structure of protein-protein recognition sites

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Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP

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