Crystal structure of a transcriptionally active Smad4 fragment (Q27621046)

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

The TGF-beta family and its composite receptors

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7 January 2021

TGF-beta related genes in development

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

TGFbeta signaling: receptors, transducers, and Mad proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Mechanism of activation of the TGF-beta receptor

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Smad6 inhibits signalling by the TGF-beta superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Smad4/DPC4 and Smad3 mediate transforming growth factor-beta (TGF-beta) signaling through direct binding to a novel TGF-beta-responsive element in the human plasminogen activator inhibitor-1 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Characterization of functional domains within Smad4/DPC4

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Somatic alterations of the DPC4 gene in human colorectal cancers in vivo

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

A structural basis for mutational inactivation of the tumour suppressor Smad4

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

The upstream activator CTF/NF1 and RNA polymerase II share a common element involved in transcriptional activation

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https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Functional differences between mammalian transcription activation domains at the yeast GAL1 promoter.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Analysis of the DNA-binding and activation properties of the human transcription factor AP-2

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

The Oct-2 glutamine-rich and proline-rich activation domains can synergize with each other or duplicates of themselves to activate transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Three classes of mammalian transcription activation domain stimulate transcription in Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Crystal structure of the human papillomavirus type 18 E2 activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Induced alpha helix in the VP16 activation domain upon binding to a human TAF

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021

Raster3D Version 2.0. A program for photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2800%2988340-9

7 January 2021