Exosome non-catalytic core subunit RRP43 YCR035C (Q27551845)

Ribosomal protein S5 domain 2-type fold

1 reference

PNPase/RNase PH domain superfamily

1 reference

Exoribonuclease, phosphorolytic domain 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

13 references

14 February 2019

Subunit architecture of multimeric complexes isolated directly from cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

RNA degradation paths in a 12-subunit nuclear exosome complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Characterization of Saccharomyces cerevisiae Nop17p, a novel Nop58p-interacting protein that is involved in Pre-rRNA processing.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Nop17 is a key R2TP factor for the assembly and maturation of box C/D snoRNP complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Utp25p, a nucleolar Saccharomyces cerevisiae protein, interacts with U3 snoRNP subunits and affects processing of the 35S pre-rRNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

A single subunit, Dis3, is essentially responsible for yeast exosome core activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Structure of an Rrp6–RNA exosome complex bound to poly(A) RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Probing genuine strong interactions and post-translational modifications in the heterogeneous yeast exosome protein complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

RNA channelling by the eukaryotic exosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

1 reference

14 February 2019

Nip7p interacts with Nop8p, an essential nucleolar protein required for 60S ribosome biogenesis, and the exosome subunit Rrp43p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

nuclear exosome (RNase complex)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

exosome (RNase complex)

2 references

1 reference

14 February 2019

cytoplasmic exosome (RNase complex)

nuclear exosome (RNase complex)

3 references

14 February 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

cytoplasmic exosome (RNase complex)

3 references

14 February 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

biological process

nonfunctional rRNA decay

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay

1 reference

14 February 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

nuclear polyadenylation-dependent rRNA catabolic process

1 reference

27 February 2018

Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25359&geneProductId=UniProtKB:P25359

nuclear polyadenylation-dependent tRNA catabolic process

nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'

1 reference

27 February 2018

Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25359&geneProductId=UniProtKB:P25359

polyadenylation-dependent snoRNA 3'-end processing

1 reference

14 February 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

RNA catabolic process

1 reference

14 February 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

ncRNA 3'-end processing

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

nuclear polyadenylation-dependent mRNA catabolic process

1 reference

27 February 2018

Regulation of NAB2 mRNA 3'-end formation requires the core exosome and the Trf4p component of the TRAMP complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25359&geneProductId=UniProtKB:P25359

nuclear-transcribed mRNA catabolic process, non-stop decay

1 reference

14 February 2019

The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

3 references

27 February 2018

Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25359&geneProductId=UniProtKB:P25359

27 February 2018

Functions of the exosome in rRNA, snoRNA and snRNA synthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25359&geneProductId=UniProtKB:P25359

27 February 2018

The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25359&geneProductId=UniProtKB:P25359

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.

mRNA catabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.

rRNA metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

poly(A)+ mRNA export from nucleus

1 reference

14 February 2019

Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

U1 snRNA 3'-end processing

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

U4 snRNA 3'-end processing

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

U5 snRNA 3'-end processing

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

exonucleolytic catabolism of deadenylated mRNA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

nuclear mRNA surveillance

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

4 references

14 February 2019

Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Functions of the exosome in rRNA, snoRNA and snRNA synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

rRNA catabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'

nuclear polyadenylation-dependent rRNA catabolic process

nuclear polyadenylation-dependent tRNA catabolic process

3 references

14 February 2019

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

A new yeast poly(A) polymerase complex involved in RNA quality control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25359

nuclear polyadenylation-dependent mRNA catabolic process

Exoribonuclease, phosphorolytic domain 1

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference